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NCT00759941 · ClinicalTrials.gov registry record · Phase 4

A Comparison of Azopt Versus Placebo Added to Xalatan in Patients With Elevated Intraocular Pressure (IOP) on a Prostaglandin

A Phase 4 study, sponsored by Alcon Research.

Completed
Registry status
Phase 4
Development phase
86
Enrollment target

NCT00759941: Completed Phase 4 study, sponsored by Alcon Research.

NCT00759941 is a Phase 4 study that has completed, run by Alcon Research. The registered enrollment target is 86 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00759941, a Phase 4 study, has completed, sponsored by Alcon Research.

COMPLETED
Registry status
Phase 4
Development phase
86 participants
Enrollment target

Study Summary

The purpose of this study was to assess the efficacy of adding Azopt dosed three times a day to Xalatan as compared to that of adding placebo to Xalatan in patients with elevated intraocular pressure.

Primary Outcome

Intraocular pressure was measured by Goldmann applanation tonometry. A negative number indicated a reduction in intraocular pressure.

Interventions

  • DRUG Placebo eye drops
  • DRUG Brinzolamide 1% ophthalmic solution (Azopt)
  • DRUG Latanoprost 0.005% ophthalmic solution (Xalatan)

Trial Details

FieldValue
Enrollment Target 86 participants
Start Date 2007-10
Est. Completion 2009-07
Phase Phase 4
Alcon Research

275 total trials

What the finished NCT00759941 record still lists

NCT00759941 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 86 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo eye drops is the first listed.

NCT00759941 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00759941 about?

NCT00759941 is a clinical study titled "A Comparison of Azopt Versus Placebo Added to Xalatan in Patients With Elevated Intraocular Pressure (IOP) on a Prostaglandin". The purpose of this study was to assess the efficacy of adding Azopt dosed three times a day to Xalatan as compared to that of adding placebo to Xalatan in patients with elevated intraocular pressure.

What is the current status of trial NCT00759941?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 86 participants. The study started on 2007-10. Estimated completion is 2009-07.

What interventions are being tested in trial NCT00759941?

The interventions under investigation include: Placebo eye drops (DRUG), Brinzolamide 1% ophthalmic solution (Azopt) (DRUG), Latanoprost 0.005% ophthalmic solution (Xalatan) (DRUG).

Who is sponsoring clinical trial NCT00759941?

This trial is sponsored by Alcon Research, which has 275 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00759941's enrollment target sits among peer trials

86 926th of 2000 higher than 1,073 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00759941, the US trial registry maintained by the National Library of Medicine. NCT00759941 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.