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NCT00759928 · ClinicalTrials.gov registry record · Phase 1
PK Trial of Sorafenib & Erlotinib in Patients With Refractory Solid Tumors
A Phase 1 study of Refractory Solid Tumors, sponsored by SCRI Development Innovations.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
- 2
- Study locations
NCT00759928: Completed Phase 1 study of Refractory Solid Tumors, sponsored by SCRI Development Innovations.
NCT00759928 is a Phase 1 study of Refractory Solid Tumors that has completed, run by SCRI Development Innovations. The registered enrollment target is 48 participants, below the 1,460-participant average among 7 other Refractory Solid Tumors trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00759928, a Phase 1 study of Refractory Solid Tumors, has completed, sponsored by SCRI Development Innovations.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
- 2
- Study locations
Study Summary
Two cohorts of patients will be enrolled: Cohort A will consist of patients who are current smokers, and Cohort B will consist of patients who are current nonsmokers. There will be 24 patients enrolled in each cohort. Nonsmokers are patients who have not consumed tobacco or nicotine-containing products for 1 year before the start of the study. Patients classified as current smokers must have smoked a minimum of 10 cigarettes per day for up to 1 year. Patients who have smoked 1-9 cigarettes per day for up to 1 year, or more than 10 cigarettes per day for less than 1 year will not be eligible for this study.
Conditions Studied
Interventions
- DRUG Sorafenib
- DRUG Erlotinib
Study Locations (2)
Florida
- Florida Cancer Specialists - Fort Myers
Tennessee
- Tennessee Oncology - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2008-10 |
| Est. Completion | 2014-06 |
| Phase | Phase 1 |
What the finished NCT00759928 record still lists
NCT00759928 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 1,460-participant average among 7 other Refractory Solid Tumors trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Refractory Solid Tumors appearing as the primary indexed condition, and to 2 interventions - of which Sorafenib is the first listed.
NCT00759928 reports a single indexed study location in Florida, Tennessee.
Frequently Asked Questions
What is clinical trial NCT00759928 about?
NCT00759928 is a clinical study titled "PK Trial of Sorafenib & Erlotinib in Patients With Refractory Solid Tumors". Two cohorts of patients will be enrolled: Cohort A will consist of patients who are current smokers, and Cohort B will consist of patients who are current nonsmokers. There will be 24 patients enrolled in each cohort. Nonsmokers are patients who have not consumed tobacco or nicotine-containing produ...
What is the current status of trial NCT00759928?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2008-10. Estimated completion is 2014-06.
What conditions does trial NCT00759928 study?
This clinical trial studies the following conditions: Refractory Solid Tumors.
What interventions are being tested in trial NCT00759928?
The interventions under investigation include: Sorafenib (DRUG), Erlotinib (DRUG).
Who is sponsoring clinical trial NCT00759928?
This trial is sponsored by SCRI Development Innovations, which has 146 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00759928 being conducted?
This trial has 2 study locations across Florida, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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