Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00758420 · ClinicalTrials.gov registry record · Phase 2
Randomized, Single Blind, Placebo Controlled, to Evaluate Efficacy and Safety of Polidocanol Injectable Foam for Treatment of Symptomatic, Visible Varicose Veins With SFJ Incompetence
A Phase 2 study of Varicose Veins, sponsored by Boston Scientific Corporation.
- Completed
- Registry status
- Phase 2
- Development phase
- 77
- Enrollment target
- 5
- Study locations
NCT00758420: Completed Phase 2 study of Varicose Veins, sponsored by Boston Scientific Corporation.
NCT00758420 is a Phase 2 study of Varicose Veins that has completed, run by Boston Scientific Corporation. The registered enrollment target is 77 participants, below the 157-participant average among 6 other Varicose Veins trials with a reported enrollment target (51% lower). The trial reports 5 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00758420, a Phase 2 study of Varicose Veins, has completed, sponsored by Boston Scientific Corporation.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 77 participants
- Enrollment target
- 5
- Study locations
Study Summary
The purpose of this study is to evaluate the effectiveness of polidocanol injectable foam in the relief of symptoms, improvement of appearance, and overall effectiveness and safety in the treatment of varicose veins compared to placebo.
Primary Outcome
The VVSymQ is a subset of the VEINES-Sym and consists of the 5 symptoms most relevant to patients. The raw score, which can range from 5 to 30, was transformed to a summary VVSymQ score that ranges from 0 (worst possible symptom health) to 100 (best symptom health) using the following formula: VVSymQ: (Transformed Score) = \[(Raw Score) - 5\] \* 4.
Conditions Studied
Interventions
- DRUG Varisolve (Polidocanol Endovenous Microfoam)
- DRUG Agitated Saline
Study Locations (5)
North Carolina
- - Charlotte
- - Winston-Salem
Arizona
- - Scottsdale
New York
- - New York
Washington
- - Bellevue
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 77 participants |
| Start Date | 2008-10 |
| Est. Completion | 2009-08 |
| Phase | Phase 2 |
What the finished NCT00758420 record still lists
NCT00758420 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 77 participants, a relatively small participant target, below the 157-participant average among 6 other Varicose Veins trials with a reported enrollment target (51% lower).
The record links to 1 condition, with Varicose Veins appearing as the primary indexed condition, and to 2 interventions - of which Varisolve (Polidocanol Endovenous Microfoam) is the first listed.
NCT00758420 lists 5 locations in 4 states (North Carolina, Arizona, New York).
Frequently Asked Questions
What is clinical trial NCT00758420 about?
NCT00758420 is a clinical study titled "Randomized, Single Blind, Placebo Controlled, to Evaluate Efficacy and Safety of Polidocanol Injectable Foam for Treatment of Symptomatic, Visible Varicose Veins With SFJ Incompetence". The purpose of this study is to evaluate the effectiveness of polidocanol injectable foam in the relief of symptoms, improvement of appearance, and overall effectiveness and safety in the treatment of varicose veins compared to placebo.
What is the current status of trial NCT00758420?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 77 participants. The study started on 2008-10. Estimated completion is 2009-08.
What conditions does trial NCT00758420 study?
This clinical trial studies the following conditions: Varicose Veins.
What interventions are being tested in trial NCT00758420?
The interventions under investigation include: Varisolve (Polidocanol Endovenous Microfoam) (DRUG), Agitated Saline (DRUG).
Who is sponsoring clinical trial NCT00758420?
This trial is sponsored by Boston Scientific Corporation, which has 280 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00758420 being conducted?
This trial has 5 study locations across Arizona, New York, North Carolina, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Varicose Veins
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
An Open-label, Single-dose Pilot Study to Evaluate Varisolve® (Polidocanol Endovenous Microfoam (PEM)) 0.125% [0.2%] for Varicose Veins
COMPLETED · Phase 2
-
Polidocanol Endovenous Microfoam (PEM) Versus Vehicle for the Treatment of Saphenofemoral Junction (SFJ) Incompetence
COMPLETED · Phase 3
-
COMFORT: A Multicenter, Open-label, Randomized, Crossover Study
COMPLETED · Phase 4
-
Retrospective Review of Saphenous Vein Incompetence: Venaseal Versus Endovenous Thermal Ablation
COMPLETED
-
Pharmacokinetic Study of Polidocanol Endovenous Microfoam (PEM)
COMPLETED · Phase 1
-
Prevalence of MTHFR Polymorphisms in Venous Disease
COMPLETED
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02127398 · 77 participants · Phase 2
Stool Transplants to Treat Refractory Clostridium Difficile Colitis
- NCT04159103 · 77 participants · Phase 1
Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia
- NCT04683003 · 77 participants · Phase 3
A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura
- NCT05004116 · 77 participants · Phase 1
A Study of Repotrectinib in Combination With Chemotherapy in Children and Young Adults With Solid Tumor Cancer
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia