Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00756457 · ClinicalTrials.gov registry record · Phase 2

Bracing and Strengthening for Posterior Tibial Tendon Dysfunction

A Phase 2 study, sponsored by Ithaca College.

Completed
Registry status
Phase 2
Development phase
39
Enrollment target

NCT00756457: Completed Phase 2 study, sponsored by Ithaca College.

NCT00756457 is a Phase 2 study that has completed, run by Ithaca College. The registered enrollment target is 39 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00756457, a Phase 2 study, has completed, sponsored by Ithaca College.

COMPLETED
Registry status
Phase 2
Development phase
39 participants
Enrollment target

Study Summary

Posterior tibial tendon dysfunction (PTTD) is a problem with the tendon connecting one of the lower leg muscles to the foot bone. PTTD can cause pain, swelling, and a flattened foot and may require surgery if left untreated. Normal treatment for PTTD includes physical therapy exercise. In treating similar conditions in the lower leg, exercises that are active, like strengthening, seem to have better results than exercises that are passive, like stretching. This study will determine whether adding strengthening exercises to a normal PTTD treatment that includes wearing a brace and stretching is more beneficial than just wearing a brace and stretching.

Primary Outcome

The Foot Function Index (FFI) is a validated disease specific questionnaire that has been used to document outcomes in uncontrolled studies of PTTD. The domains of the 23 item FFI questionnaire include pain, disability, and activity limitations. The scale was originally validated in subjects with foot problems related to rheumatoid arthritis patients, and has subsequently been used to measure outcomes for a variety of foot and ankle problems including plantar fasciitis, diabetes, and PTTD. In cl

Interventions

  • DEVICE Bracing
  • OTHER Strengthening exercises
  • OTHER Stretching exercises

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 2007-07
Est. Completion 2008-09
Phase Phase 2
Ithaca College

5 total trials

What the finished NCT00756457 record still lists

NCT00756457 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower).

The record links to 0 conditions, and to 3 interventions - of which Bracing is the first listed.

NCT00756457 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00756457 about?

NCT00756457 is a clinical study titled "Bracing and Strengthening for Posterior Tibial Tendon Dysfunction". Posterior tibial tendon dysfunction (PTTD) is a problem with the tendon connecting one of the lower leg muscles to the foot bone. PTTD can cause pain, swelling, and a flattened foot and may require surgery if left untreated. Normal treatment for PTTD includes physical therapy exercise. In treating s...

What is the current status of trial NCT00756457?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 39 participants. The study started on 2007-07. Estimated completion is 2008-09.

What interventions are being tested in trial NCT00756457?

The interventions under investigation include: Bracing (DEVICE), Strengthening exercises (OTHER), Stretching exercises (OTHER).

Who is sponsoring clinical trial NCT00756457?

This trial is sponsored by Ithaca College, which has 5 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00756457's enrollment target sits among peer trials

39 1459th of 2000 higher than 534 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03465592 · 39 participants · Phase 1

    Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma

  • NCT03961776 · 39 participants

    Monitoring Treatment Response With On-board DWI During Neo-adjuvant Chemo-radiation for Rectal Cancer Using Magnetic Resonance-guided-radiotherapy Systems

  • NCT04050280 · 39 participants · Phase 2

    CLAG-GO for Patients With Persistent, Relapsed or Refractory AML

  • NCT04190862 · 39 participants · Phase 1

    E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00756457, the US trial registry maintained by the National Library of Medicine. NCT00756457 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.