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NCT00755911 · ClinicalTrials.gov registry record · Phase 1
Treatment of Alveolar Bone Defects Using Aastrom Biosciences Autologous Tissue Repair Cell Therapy
A Phase 1 study, sponsored by University of Michigan.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT00755911: Completed Phase 1 study, sponsored by University of Michigan.
NCT00755911 is a Phase 1 study that has completed, run by University of Michigan. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00755911, a Phase 1 study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
The purpose of this research is to determine if a subject's own bone marrow tissue can help regenerate bone in the area of his/her jaw where a tooth has been removed using Tissue Repair Cell (TRC) Therapy.
Primary Outcome
The primary objective of this study is to determine whether the placement of Tissue Repair Cells (TRCs) at the time of tooth extraction can safely and effectively promote bone regeneration in alveolar bone defects created by tooth extraction. * Safety was assessed through adverse event reporting * Bone regeneration was assessed through measures of bone mineral density and bone volume fraction of biopsied regenerated bone tissue. Bone regeneration was also measured through radiographic analysis
Interventions
- DEVICE Control
- BIOLOGICAL Tissue Repair Cells (TRC)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2008-06 |
| Est. Completion | 2012-05 |
| Phase | Phase 1 |
What the finished NCT00755911 record still lists
NCT00755911 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 2 interventions - of which Control is the first listed.
NCT00755911 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00755911 about?
NCT00755911 is a clinical study titled "Treatment of Alveolar Bone Defects Using Aastrom Biosciences Autologous Tissue Repair Cell Therapy". The purpose of this research is to determine if a subject's own bone marrow tissue can help regenerate bone in the area of his/her jaw where a tooth has been removed using Tissue Repair Cell (TRC) Therapy.
What is the current status of trial NCT00755911?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2008-06. Estimated completion is 2012-05.
What interventions are being tested in trial NCT00755911?
The interventions under investigation include: Control (DEVICE), Tissue Repair Cells (TRC) (BIOLOGICAL).
Who is sponsoring clinical trial NCT00755911?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00755911's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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