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NCT00748878 · ClinicalTrials.gov registry record
Platelet Function During ECMO (Extra Corporeal Membrane Oxygenation)
A clinical trial, sponsored by University of Utah.
- Completed
- Registry status
- 5
- Enrollment target
NCT00748878 is a clinical trial that has completed, run by University of Utah. The registered enrollment target is 5 participants.
The verdict
NCT00748878 has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- 5 participants
- Enrollment target
Study Summary
Platelet transfusions are routinely administered during neonatal ECMO, with an average of 1.3 platelet transfusions per day being administered while a patient is undergoing ECMO treatment. The cause of thrombocytopenia during ECMO largely involves platelet adherence to the oxygenator membrane. Platelet transfusions carry risks such as infections with bacteria or yeast, and development or worsening of pulmonary hypertension. It is likely that if fewer platelet transfusions can be administered during the ECMO run, the cumulative adverse effects of platelet transfusions would diminish and patient outcomes improve. In order to better understand platelet function during ECMO, the investigators plan to serially determine the circulating platelet mass, plasma platelet factor 4 concentration, megakaryocyte mass (estimated by plasma thrombopoietin concentration), and platelet function as quantified by PFA100. Any patient on ECMO will be eligible for this pilot study of 5 patients. By understanding changes in platelet function, we hope to design a future study that may modify the frequency or need for platelet transfusions during ECMO.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2008-06 |
| Est. Completion | 2013-06 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00748878
The ClinicalTrials.gov registry entry for NCT00748878 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Utah, which has 818 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT00748878 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00748878 about?
NCT00748878 is a clinical study titled "Platelet Function During ECMO (Extra Corporeal Membrane Oxygenation)". Platelet transfusions are routinely administered during neonatal ECMO, with an average of 1.3 platelet transfusions per day being administered while a patient is undergoing ECMO treatment. The cause of thrombocytopenia during ECMO largely involves platelet adherence to the oxygenator membrane. Plate...
What is the current status of trial NCT00748878?
This trial is currently completed. The enrollment target is 5 participants. The study started on 2008-06. Estimated completion is 2013-06.
Who is sponsoring clinical trial NCT00748878?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
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