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NCT00748228 · ClinicalTrials.gov registry record · NA
Dopamine in Orthostatic Tolerance
A NA study, sponsored by Vanderbilt University.
- Terminated
- Registry status
- NA
- Development phase
- 22
- Enrollment target
NCT00748228: Clinical Trial NA study, sponsored by Vanderbilt University.
NCT00748228 is a NA study that was terminated before completion, run by Vanderbilt University. The registered enrollment target is 22 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00748228, a NA study, was terminated before completion, sponsored by Vanderbilt University.
- TERMINATED
- Registry status
- NA
- Development phase
- 22 participants
- Enrollment target
Study Summary
One goal of this study is to determine whether people with different amounts of dopamine-beta-hydroxylase (DBH) have different responses to events that affect blood pressure and heart rate. We will also study whether increasing dietary salt improves symptoms during upright posture. Finally, we will examine whether the dietary sodium level influences serum DBH activity and whether DBH level influences the response to sodium. DBH levels and the function of the sympathetic or involuntary nervous system will be assessed in normal volunteers and in patients with postural tachycardia syndrome (POTS).
Interventions
- DIETARY_SUPPLEMENT dietary sodium
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2004-11 |
| Est. Completion | 2012-07 |
| Phase | NA |
Why NCT00748228 stopped before completion
NCT00748228 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which dietary sodium is the first listed.
NCT00748228 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00748228 about?
NCT00748228 is a clinical study titled "Dopamine in Orthostatic Tolerance". One goal of this study is to determine whether people with different amounts of dopamine-beta-hydroxylase (DBH) have different responses to events that affect blood pressure and heart rate. We will also study whether increasing dietary salt improves symptoms during upright posture. Finally, we will ...
What is the current status of trial NCT00748228?
This trial is currently terminated. It is a NA study. The enrollment target is 22 participants. The study started on 2004-11. Estimated completion is 2012-07.
What interventions are being tested in trial NCT00748228?
The interventions under investigation include: dietary sodium (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT00748228?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00748228's enrollment target sits among peer trials
22 1756th of 2000 higher than 239 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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