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NCT00747240 · ClinicalTrials.gov registry record
Platelet-activating Factor Acetylhydrolase (Paf-ah) Gene Expression
A clinical trial, sponsored by University of Utah.
- Completed
- Registry status
- 139
- Enrollment target
NCT00747240: Completed study, sponsored by University of Utah.
NCT00747240 is a clinical trial that has completed, run by University of Utah. The registered enrollment target is 139 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00747240 has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- 139 participants
- Enrollment target
Study Summary
This is a prospective observational study to determine whether there is an association between the presence of platelet-activating factor acetylhydrolase (PAF-AH) gene polymorphisms and the development of chronic lung disease in very low birth wight infants. Infants \< 1500 grams at birth who require mechanical ventilation will be enrolled in the first 5 days of life after obtaining informed consent. A total of 1 ml of blood will be drawn and utilized for isolation of DNA for genotyping and for measurement of PAF-AH activity in serum.
Primary Outcome
CLD will be defined as an oxygen requirement and abnormal x-ray findings. Investigations will compare outcomes of participants with genotypic variants of PAF-AH and those without known PAF-AH polymorphisms. Also, participant with biochemical evidence of PAF-AH dysregulation will be compared to those with normal PAF-AH protein and PAF concentrations.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 139 participants |
| Start Date | 2002-02 |
| Est. Completion | 2014-12 |
What the finished NCT00747240 record still lists
NCT00747240 is an observational study that tracks outcomes without assigning an intervention. The registered 139 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00747240 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00747240 about?
NCT00747240 is a clinical study titled "Platelet-activating Factor Acetylhydrolase (Paf-ah) Gene Expression". This is a prospective observational study to determine whether there is an association between the presence of platelet-activating factor acetylhydrolase (PAF-AH) gene polymorphisms and the development of chronic lung disease in very low birth wight infants. Infants \< 1500 grams at birth who requir...
What is the current status of trial NCT00747240?
This trial is currently completed. The enrollment target is 139 participants. The study started on 2002-02. Estimated completion is 2014-12.
Who is sponsoring clinical trial NCT00747240?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
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