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NCT00743210 · ClinicalTrials.gov registry record · Phase 1
Oral L-Citrulline and ADMA in Pregnancy
A Phase 1 study, sponsored by University of Pittsburgh.
- Completed
- Registry status
- Phase 1
- Development phase
- 41
- Enrollment target
NCT00743210: Completed Phase 1 study, sponsored by University of Pittsburgh.
NCT00743210 is a Phase 1 study that has completed, run by University of Pittsburgh. The registered enrollment target is 41 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00743210, a Phase 1 study, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 41 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if oral of L-citrulline (3 grams/day) for 3 weeks provided in mid-pregnancy to obese subjects will decrease the plasma ADMA/L-arginine ratio, lower maternal blood pressure, improve endothelial-dependent vascular function and peripheral vascular stiffness, and improve uterine artery Doppler resistance and flow.
Interventions
- DRUG Placebo
- DRUG L-citrulline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2010-01 |
| Est. Completion | 2013-06 |
| Phase | Phase 1 |
What the finished NCT00743210 record still lists
NCT00743210 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00743210 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00743210 about?
NCT00743210 is a clinical study titled "Oral L-Citrulline and ADMA in Pregnancy". The purpose of this study is to determine if oral of L-citrulline (3 grams/day) for 3 weeks provided in mid-pregnancy to obese subjects will decrease the plasma ADMA/L-arginine ratio, lower maternal blood pressure, improve endothelial-dependent vascular function and peripheral vascular stiffness, an...
What is the current status of trial NCT00743210?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2010-01. Estimated completion is 2013-06.
What interventions are being tested in trial NCT00743210?
The interventions under investigation include: Placebo (DRUG), L-citrulline (DRUG).
Who is sponsoring clinical trial NCT00743210?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00743210's enrollment target sits among peer trials
41 1125th of 2000 higher than 871 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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