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NCT00743197 · ClinicalTrials.gov registry record · NA
Women With Chest Pain and Normal Coronary Arteries Study
A NA study, sponsored by Northwestern University.
- Terminated
- Registry status
- NA
- Development phase
- 3
- Enrollment target
NCT00743197: Clinical Trial NA study, sponsored by Northwestern University.
NCT00743197 is a NA study that was terminated before completion, run by Northwestern University. The registered enrollment target is 3 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00743197, a NA study, was terminated before completion, sponsored by Northwestern University.
- TERMINATED
- Registry status
- NA
- Development phase
- 3 participants
- Enrollment target
Study Summary
The purpose of this study is to compare the effectiveness of standard medical therapy versus usual care in women with chest pain, coronary endothelial dysfunction and unblocked coronary arteries. Coronary endothelial dysfunction (CED) is a condition in which the layers of cells around the heart do not function properly and is believed to be key factor in the development of atherosclerosis (fat deposits in arteries). In addition, CED is associated with an increased risk for future cardiovascular events, such as heart attack and stroke. A coronary angiogram allows physicians to see if any of the arteries in the heart are blocked, usually by fatty plaque. In many instances, angiograms in women experiencing chest pain do not show evidence of coronary disease (free of significant plaque build-up). Currently, there is no standard of care treatment plan for patients with normal coronary arteries, despite symptoms of chest pain, and as a result these patients may not receive medical treatment. However, these women often return to their physicians more than once with chest pain and go through a similar battery of tests.
Primary Outcome
The purpose of this study is to compare the effectiveness of standard medical therapy versus usual care in women with chest pain (CP), coronary endothelial dysfunction (CED) and unblocked coronary arteries. CED is a condition in which the layers of cells around the heart do not function properly and is believed to be a key factor in the development of atherosclerosis (fat deposits in arteries). In addition, CED is associated with an increased risk for suture cardiovascular events, such as heart
Interventions
- DRUG Aspirin
- DRUG Simvastatin
- DRUG Lisinopril
- DRUG Lovaza
- BEHAVIORAL Therapeutic Lifestyle Changes
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2008-05 |
| Est. Completion | 2010-05 |
| Phase | NA |
Why NCT00743197 stopped before completion
NCT00743197 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 5 interventions - of which Aspirin is the first listed.
NCT00743197 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00743197 about?
NCT00743197 is a clinical study titled "Women With Chest Pain and Normal Coronary Arteries Study". The purpose of this study is to compare the effectiveness of standard medical therapy versus usual care in women with chest pain, coronary endothelial dysfunction and unblocked coronary arteries. Coronary endothelial dysfunction (CED) is a condition in which the layers of cells around the heart do ...
What is the current status of trial NCT00743197?
This trial is currently terminated. It is a NA study. The enrollment target is 3 participants. The study started on 2008-05. Estimated completion is 2010-05.
What interventions are being tested in trial NCT00743197?
The interventions under investigation include: Aspirin (DRUG), Simvastatin (DRUG), Lisinopril (DRUG), Lovaza (DRUG), Therapeutic Lifestyle Changes (BEHAVIORAL).
Who is sponsoring clinical trial NCT00743197?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00743197's enrollment target sits among peer trials
3 1996th of 2000 higher than 4 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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