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NCT00742391 · ClinicalTrials.gov registry record · Phase 3
A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations
A Phase 3 study, sponsored by Peplin.
- Completed
- Registry status
- Phase 3
- Development phase
- 255
- Enrollment target
NCT00742391: Completed Phase 3 study, sponsored by Peplin.
NCT00742391 is a Phase 3 study that has completed, run by Peplin. The registered enrollment target is 255 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00742391, a Phase 3 study, has completed, sponsored by Peplin.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 255 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether topical application of PEP005 is effective for the treatment of actinic keratoses.
Primary Outcome
Complete clearance rate of actinic keratosis (AK) lesions defined as the proportion of patients with no clinically visible AK lesions in the selected treatment area.
Interventions
- DRUG Vehicle gel
- DRUG PEP005 (ingenol mebutate) Gel
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 255 participants |
| Start Date | 2008-09 |
| Est. Completion | 2009-02 |
| Phase | Phase 3 |
What the finished NCT00742391 record still lists
NCT00742391 is an interventional study that assigns participants to a tested intervention. The registered 255 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 2 interventions - of which Vehicle gel is the first listed.
NCT00742391 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00742391 about?
NCT00742391 is a clinical study titled "A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations". The purpose of this study is to determine whether topical application of PEP005 is effective for the treatment of actinic keratoses.
What is the current status of trial NCT00742391?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 255 participants. The study started on 2008-09. Estimated completion is 2009-02.
What interventions are being tested in trial NCT00742391?
The interventions under investigation include: Vehicle gel (DRUG), PEP005 (ingenol mebutate) Gel (DRUG).
Who is sponsoring clinical trial NCT00742391?
This trial is sponsored by Peplin, which has 19 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00742391's enrollment target sits among peer trials
255 1242nd of 2000 higher than 756 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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