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NCT00741026 · ClinicalTrials.gov registry record · NA
A Crossover Study of the Acute Effects of Olanzapine in Healthy Volunteers
A NA study, sponsored by Milton S. Hershey Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT00741026: Completed NA study, sponsored by Milton S. Hershey Medical Center.
NCT00741026 is a NA study that has completed, run by Milton S. Hershey Medical Center. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00741026, a NA study, has completed, sponsored by Milton S. Hershey Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
The purpose of this clinical research study is to examine the acute hormonal and metabolic effects of the drug olanzapine, as well as appetite effects, in healthy volunteers. The hypotheses to be tested are that: (1) Olanzapine rapidly attenuates plasma leptin and (2) rapidly alters glucose tolerance in healthy volunteers. These questions will be answered by having volunteers undergo two glucose tolerance tests in a crossover study design.
Primary Outcome
Leptin following placebo or olanzapine treatment
Interventions
- DRUG Placebo
- DRUG Olanzapine 10 mg po qhs for 3 days
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2008-08 |
| Est. Completion | 2011-05 |
| Phase | NA |
What the finished NCT00741026 record still lists
NCT00741026 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00741026 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00741026 about?
NCT00741026 is a clinical study titled "A Crossover Study of the Acute Effects of Olanzapine in Healthy Volunteers". The purpose of this clinical research study is to examine the acute hormonal and metabolic effects of the drug olanzapine, as well as appetite effects, in healthy volunteers. The hypotheses to be tested are that: (1) Olanzapine rapidly attenuates plasma leptin and (2) rapidly alters glucose toleranc...
What is the current status of trial NCT00741026?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2008-08. Estimated completion is 2011-05.
What interventions are being tested in trial NCT00741026?
The interventions under investigation include: Placebo (DRUG), Olanzapine 10 mg po qhs for 3 days (DRUG).
Who is sponsoring clinical trial NCT00741026?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00741026's enrollment target sits among peer trials
15 1881st of 2000 higher than 92 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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