Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00740181 · ClinicalTrials.gov registry record · Phase 2
Decitabine, Cytarabine, GCSF for Refractory AML/MDS
A Phase 2 study, sponsored by Brown University.
- Terminated
- Registry status
- Phase 2
- Development phase
- 9
- Enrollment target
NCT00740181: Clinical Trial Phase 2 study, sponsored by Brown University.
NCT00740181 is a Phase 2 study that was terminated before completion, run by Brown University. The registered enrollment target is 9 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00740181, a Phase 2 study, was terminated before completion, sponsored by Brown University.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 9 participants
- Enrollment target
Study Summary
This study will determine the activity of decitabine, low dose cytarabine (ARA-C) and G-CSF for patients with myelodysplasia and leukemia.
Primary Outcome
Complete Response/Complete Remission: Complete remission (CR) is defined as the presence of all of the following: * Peripheral blood - No leukemic blasts present. * No extramedullary findings of leukemia or disappearance of such (i.e. CNS or soft tissue involvement) * Bone marrow * No Auer rods * Less than 5% blast cells. * CBC and bone marrow criteria must be met within one week of each other. * Hemoglobin 9g/dl or greater * Neutrophil count \>1000 and platelet count \>100,000. * RBC Transfus
Interventions
- DRUG chemotherapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2008-08 |
| Est. Completion | 2010-04 |
| Phase | Phase 2 |
Why NCT00740181 stopped before completion
NCT00740181 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 1 intervention - of which chemotherapy is the first listed.
NCT00740181 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00740181 about?
NCT00740181 is a clinical study titled "Decitabine, Cytarabine, GCSF for Refractory AML/MDS". This study will determine the activity of decitabine, low dose cytarabine (ARA-C) and G-CSF for patients with myelodysplasia and leukemia.
What is the current status of trial NCT00740181?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 9 participants. The study started on 2008-08. Estimated completion is 2010-04.
What interventions are being tested in trial NCT00740181?
The interventions under investigation include: chemotherapy (DRUG).
Who is sponsoring clinical trial NCT00740181?
This trial is sponsored by Brown University, which has 231 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00740181's enrollment target sits among peer trials
9 1989th of 2000 higher than 11 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia