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NCT00729300 · ClinicalTrials.gov registry record · Phase 1
A Study of the Relationship Between Disulfiram and Cocaine Self-administration.
A Phase 1 study, sponsored by Baylor College of Medicine.
- Completed
- Registry status
- Phase 1
- Development phase
- 52
- Enrollment target
NCT00729300 is a Phase 1 study that has completed, run by Baylor College of Medicine. The registered enrollment target is 52 participants.
The verdict
NCT00729300, a Phase 1 study, has completed, sponsored by Baylor College of Medicine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 52 participants
- Enrollment target
Study Summary
The problem of cocaine dependence remains a major medical, social, and legal concern. Several studies have suggested that disulfiram may be beneficial for the treatment of cocaine dependence. A common assumption has been that disulfiram treatment, by increasing DA availability, enhances the aversive aspects of stimulants. This study aims to measure plasma activity in those with the C/C DBH genotype, which is associated with higher DBH activity subsequently making the disulfiram treatment more effective, as well as determine the effects of treatment with disulfiram on cocaine self-administration using a human laboratory model of cocaine self-administration.
Interventions
- DRUG placebo
- DRUG disulfiram
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2006-04 |
| Est. Completion | 2016-06 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00729300
The ClinicalTrials.gov registry entry for NCT00729300 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Baylor College of Medicine, which has 616 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.
NCT00729300 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00729300 about?
NCT00729300 is a clinical study titled "A Study of the Relationship Between Disulfiram and Cocaine Self-administration.". The problem of cocaine dependence remains a major medical, social, and legal concern. Several studies have suggested that disulfiram may be beneficial for the treatment of cocaine dependence. A common assumption has been that disulfiram treatment, by increasing DA availability, enhances the aversive...
What is the current status of trial NCT00729300?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 52 participants. The study started on 2006-04. Estimated completion is 2016-06.
What interventions are being tested in trial NCT00729300?
The interventions under investigation include: placebo (DRUG), disulfiram (DRUG).
Who is sponsoring clinical trial NCT00729300?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
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