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NCT00726830 · ClinicalTrials.gov registry record · NA

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

A NA study, sponsored by M.D. Anderson Cancer Center.

Terminated
Registry status
NA
Development phase
1
Enrollment target

NCT00726830: Clinical Trial NA study, sponsored by M.D. Anderson Cancer Center.

NCT00726830 is a NA study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 1 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00726830, a NA study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.

TERMINATED
Registry status
NA
Development phase
1 participants
Enrollment target

Study Summary

RATIONALE: Methadone, morphine, or oxycodone may help relieve pain caused by cancer. It is not yet known whether methadone is more effective than morphine or oxycodone in treating pain in patients with cancer. PURPOSE: This randomized clinical trial is studying methadone to see how well it works compared with morphine or oxycodone in treating pain in patients with cancer.

Primary Outcome

MDASI questionnaire completed on days 8, 15, and 22 after enrollment. The 'primary success' is defined as a 3-point reduction in pain score on the MDASI. Scores from baseline and from four weeks later compared using the MDASI average pain intensity on a scale of 0 (no pain) to 10 (worst pain).

Interventions

  • DRUG morphine sulfate
  • DRUG oxycodone hydrochloride
  • DRUG methadone hydrochloride

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2009-03
Est. Completion 2010-10
Phase NA
M.D. Anderson Cancer Center

2,692 total trials

Why NCT00726830 stopped before completion

NCT00726830 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 3 interventions - of which morphine sulfate is the first listed.

NCT00726830 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00726830 about?

NCT00726830 is a clinical study titled "Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer". RATIONALE: Methadone, morphine, or oxycodone may help relieve pain caused by cancer. It is not yet known whether methadone is more effective than morphine or oxycodone in treating pain in patients with cancer. PURPOSE: This randomized clinical trial is studying methadone to see how well it works co...

What is the current status of trial NCT00726830?

This trial is currently terminated. It is a NA study. The enrollment target is 1 participants. The study started on 2009-03. Estimated completion is 2010-10.

What interventions are being tested in trial NCT00726830?

The interventions under investigation include: morphine sulfate (DRUG), oxycodone hydrochloride (DRUG), methadone hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00726830?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00726830's enrollment target sits among peer trials

1 2001st of 2000 the lowest of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00726830, the US trial registry maintained by the National Library of Medicine. NCT00726830 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.