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NCT00721877 · ClinicalTrials.gov registry record · Phase 1
Resveratrol in Healthy Adult Participants
A Phase 1 study, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 1
- Development phase
- 42
- Enrollment target
NCT00721877: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).
NCT00721877 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 42 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00721877, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 42 participants
- Enrollment target
Study Summary
Resveratrol may prevent cancer in healthy people. Studying samples of blood and urine in the laboratory from participants who are taking resveratrol may help doctors learn more about how this drug is used by the body. This phase I trial is studying the side effects of resveratrol and to see how it works in healthy adult participants.
Primary Outcome
Will be assessed by a comparison of CYP enzyme activities from baseline to end of resveratrol intervention. CYP1A2, 2D6, 2C9, and 3A4 activity will be assessed by plasma paraxanthine/caffeine ratio, urinary dextromethorphan/dextrophan ratio, urinary losartan/losartan metabolite ratio, and area under the plasma buspirone concentration-time curve, respectively. The primary analysis will consist of paired t-tests of differences in log values from baseline to end of intervention (equivalent to log o
Interventions
- OTHER laboratory biomarker analysis
- OTHER pharmacological study
- DRUG resveratrol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2008-08 |
| Est. Completion | 2009-07 |
| Phase | Phase 1 |
What the finished NCT00721877 record still lists
NCT00721877 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% lower).
The record links to 0 conditions, and to 3 interventions - of which laboratory biomarker analysis is the first listed.
NCT00721877 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00721877 about?
NCT00721877 is a clinical study titled "Resveratrol in Healthy Adult Participants". Resveratrol may prevent cancer in healthy people. Studying samples of blood and urine in the laboratory from participants who are taking resveratrol may help doctors learn more about how this drug is used by the body. This phase I trial is studying the side effects of resveratrol and to see how it w...
What is the current status of trial NCT00721877?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 42 participants. The study started on 2008-08. Estimated completion is 2009-07.
What interventions are being tested in trial NCT00721877?
The interventions under investigation include: laboratory biomarker analysis (OTHER), pharmacological study (OTHER), resveratrol (DRUG).
Who is sponsoring clinical trial NCT00721877?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00721877's enrollment target sits among peer trials
42 1105th of 2000 higher than 876 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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