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NCT00712491 · ClinicalTrials.gov registry record · Phase 1
Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular Degeneration
A Phase 1 study, sponsored by Santen.
- Terminated
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT00712491: Clinical Trial Phase 1 study, sponsored by Santen.
NCT00712491 is a Phase 1 study that was terminated before completion, run by Santen. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00712491, a Phase 1 study, was terminated before completion, sponsored by Santen.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the safety and efficacy of an ocular sirolimus (rapamycin) formulation via different injection routes in patients with treatment-naive sub-foveal choroidal neovascularization secondary to age-related macular degeneration.
Interventions
- DRUG Sirolimus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2008-09 |
| Est. Completion | 2010-03 |
| Phase | Phase 1 |
Why NCT00712491 stopped before completion
NCT00712491 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 1 intervention - of which Sirolimus is the first listed.
NCT00712491 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00712491 about?
NCT00712491 is a clinical study titled "Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular Degeneration". The purpose of this study is to determine the safety and efficacy of an ocular sirolimus (rapamycin) formulation via different injection routes in patients with treatment-naive sub-foveal choroidal neovascularization secondary to age-related macular degeneration.
What is the current status of trial NCT00712491?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2008-09. Estimated completion is 2010-03.
What interventions are being tested in trial NCT00712491?
The interventions under investigation include: Sirolimus (DRUG).
Who is sponsoring clinical trial NCT00712491?
This trial is sponsored by Santen, which has 32 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00712491's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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