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NCT00708487 · ClinicalTrials.gov registry record · NA
Live Births With Low Oxygen Blastocyst Culture
A NA study, sponsored by Texas Health Resources.
- Completed
- Registry status
- NA
- Development phase
- 230
- Enrollment target
NCT00708487: Completed NA study, sponsored by Texas Health Resources.
NCT00708487 is a NA study that has completed, run by Texas Health Resources. The registered enrollment target is 230 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (84% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00708487, a NA study, has completed, sponsored by Texas Health Resources.
- COMPLETED
- Registry status
- NA
- Development phase
- 230 participants
- Enrollment target
Study Summary
The potentially damaging effect of free O2 radicals to cultured embryos may be reduced by adding scavengers to the culture media or by reducing the incubator O2 levels. However, lowering the O2 in the culture environment can be expensive, troublesome and may not be justifiable. The objective of this study is to evaluate the effect of lowered incubator O2 tension on live birth rates in a predominately day-5 embryo transfer program. The hypothesis of this study is that a lowered (more physiological)oxygen concentration in embryo culture incubators will increase live birth rates for in vitro fertilization patients. 230 first-cycle women undergoing routine IVF or ICSI with ejaculated sperm will be randomized in a prospective clinical trial and stratified for patient age and physician. Embryos of patients will be randomly assigned for culture in either a 21% O2 (atmospheric) or 5% O2 (reduced) environment. Clinical endpoints monitored will be rates of implantation, clinical pregnancy, live birth and blastocyst cryopreservation.
Interventions
- OTHER Embryo incubator oxygen concentration
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 230 participants |
| Start Date | 1999-08 |
| Est. Completion | 2001-08 |
| Phase | NA |
What the finished NCT00708487 record still lists
NCT00708487 is an interventional study that assigns participants to a tested intervention. The registered 230 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (84% lower).
The record links to 0 conditions, and to 1 intervention - of which Embryo incubator oxygen concentration is the first listed.
NCT00708487 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00708487 about?
NCT00708487 is a clinical study titled "Live Births With Low Oxygen Blastocyst Culture". The potentially damaging effect of free O2 radicals to cultured embryos may be reduced by adding scavengers to the culture media or by reducing the incubator O2 levels. However, lowering the O2 in the culture environment can be expensive, troublesome and may not be justifiable. The objective of this...
What is the current status of trial NCT00708487?
This trial is currently completed. It is a NA study. The enrollment target is 230 participants. The study started on 1999-08. Estimated completion is 2001-08.
What interventions are being tested in trial NCT00708487?
The interventions under investigation include: Embryo incubator oxygen concentration (OTHER).
Who is sponsoring clinical trial NCT00708487?
This trial is sponsored by Texas Health Resources, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00708487's enrollment target sits among peer trials
230 465th of 2000 higher than 1,533 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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