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NCT00707265 · ClinicalTrials.gov registry record · Phase 3
rhBMP-2/CRM/CD HORIZON® Spinal System Pivotal Study
A Phase 3 study, sponsored by Medtronic Spinal and Biologics.
- Completed
- Registry status
- Phase 3
- Development phase
- 463
- Enrollment target
NCT00707265: Completed Phase 3 study, sponsored by Medtronic Spinal and Biologics.
NCT00707265 is a Phase 3 study that has completed, run by Medtronic Spinal and Biologics. The registered enrollment target is 463 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00707265, a Phase 3 study, has completed, sponsored by Medtronic Spinal and Biologics.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 463 participants
- Enrollment target
Study Summary
The purpose of this study was to evaluate the rhBMP-2/CRM/CD HORIZON® Spinal System as a method of facilitating spinal fusion in patients with degenerative disc disease.
Primary Outcome
A patient will be considered an overall success if all of the following conditions are met: 1. fusion; 2. pain/disability (Oswestry) improvement; 3. maintenance or improvement in neurological status; 4. no serious adverse event classified as implant associated or implant/surgical procedure associated; 5. no additional surgical procedure classified as a "failure."
Interventions
- DEVICE rhBMP-2/CRM/CD HORIZON® Spinal System
- DEVICE Autograft/CD HORIZON® Spinal System
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 463 participants |
| Start Date | 2002-03 |
| Est. Completion | 2010-02 |
| Phase | Phase 3 |
What the finished NCT00707265 record still lists
NCT00707265 is an interventional study that assigns participants to a tested intervention. The registered 463 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 2 interventions - of which rhBMP-2/CRM/CD HORIZON® Spinal System is the first listed.
NCT00707265 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00707265 about?
NCT00707265 is a clinical study titled "rhBMP-2/CRM/CD HORIZON® Spinal System Pivotal Study". The purpose of this study was to evaluate the rhBMP-2/CRM/CD HORIZON® Spinal System as a method of facilitating spinal fusion in patients with degenerative disc disease.
What is the current status of trial NCT00707265?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 463 participants. The study started on 2002-03. Estimated completion is 2010-02.
What interventions are being tested in trial NCT00707265?
The interventions under investigation include: rhBMP-2/CRM/CD HORIZON® Spinal System (DEVICE), Autograft/CD HORIZON® Spinal System (DEVICE).
Who is sponsoring clinical trial NCT00707265?
This trial is sponsored by Medtronic Spinal and Biologics, which has 26 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00707265's enrollment target sits among peer trials
463 821st of 2000 higher than 1,180 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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