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NCT00706836 · ClinicalTrials.gov registry record · Phase 4
PharmacofMRI of Anxiolytic Medications (Pregabalin)
A Phase 4 study, sponsored by University of California, San Diego.
- Completed
- Registry status
- Phase 4
- Development phase
- 16
- Enrollment target
NCT00706836: Completed Phase 4 study, sponsored by University of California, San Diego.
NCT00706836 is a Phase 4 study that has completed, run by University of California, San Diego. The registered enrollment target is 16 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00706836, a Phase 4 study, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 16 participants
- Enrollment target
Study Summary
The purpose of this study is to use functional magnetic resonance imaging (fMRI) in healthy controls to examine the acute effects of certain anxiolytic medications on brain function. In this case, the medication pregabalin will be used. The investigators hypothesize that pregabalin (at doses of 50 mg and 200 mg, versus placebo) will yield a reduction in amygdala and insula activity (in a dose-dependent fashion) during emotion processing using fMRI.
Primary Outcome
Region of Interest (ROI) analysis of contrast of doses (high and low) of pregabalin vs placebo on brain activity at rest and during emotional stimuli using fMRI and clinical scales.
Interventions
- DRUG placebo
- DRUG Pregabalin 50mg
- DRUG Pregabalin 200 MG
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2008-06 |
| Est. Completion | 2008-12 |
| Phase | Phase 4 |
What the finished NCT00706836 record still lists
NCT00706836 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 3 interventions - of which placebo is the first listed.
NCT00706836 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00706836 about?
NCT00706836 is a clinical study titled "PharmacofMRI of Anxiolytic Medications (Pregabalin)". The purpose of this study is to use functional magnetic resonance imaging (fMRI) in healthy controls to examine the acute effects of certain anxiolytic medications on brain function. In this case, the medication pregabalin will be used. The investigators hypothesize that pregabalin (at doses of 50 m...
What is the current status of trial NCT00706836?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 16 participants. The study started on 2008-06. Estimated completion is 2008-12.
What interventions are being tested in trial NCT00706836?
The interventions under investigation include: placebo (DRUG), Pregabalin 50mg (DRUG), Pregabalin 200 MG (DRUG).
Who is sponsoring clinical trial NCT00706836?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00706836's enrollment target sits among peer trials
16 1869th of 2000 higher than 121 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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