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NCT00705341 · ClinicalTrials.gov registry record · Phase 4
MethaCholine Bronchoprovocation Study (MeCIS)
A Phase 4 study, sponsored by Johns Hopkins Bloomberg School of Public Health.
- Completed
- Registry status
- Phase 4
- Development phase
- 219
- Enrollment target
NCT00705341: Completed Phase 4 study, sponsored by Johns Hopkins Bloomberg School of Public Health.
NCT00705341 is a Phase 4 study that has completed, run by Johns Hopkins Bloomberg School of Public Health. The registered enrollment target is 219 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00705341, a Phase 4 study, has completed, sponsored by Johns Hopkins Bloomberg School of Public Health.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 219 participants
- Enrollment target
Study Summary
The purpose of this research is to evaluate the methacholine challenge test as an accurate indicator of asthma in patients receiving treatment for asthma. Phase 1 on the study compares methacholine challenge test results from asthma patients to those from people who do not have asthma. In phase 2, test results for people with asthma on low dose inhaled corticosteroid will be compared to results on high dose inhaled corticosteroids. Both males and females with stable asthma (asthma participants) and without asthma (controls) enrolled. Participants will be between 12 and 69 years of age.
Primary Outcome
Presence and degree of airway hyperresponsiveness assessed by methacholine challenge test post-diluent baseline (PC20) after medication holds; PC20 is the methacholine dose at which the amount of air expired in the first second during a forced expiratory maneuver is reduced by 20%; value represents change in baseline to 4 weeks
Interventions
- DRUG fluticasone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 219 participants |
| Start Date | 2009-01 |
| Est. Completion | 2010-02 |
| Phase | Phase 4 |
What the finished NCT00705341 record still lists
NCT00705341 is an interventional study that assigns participants to a tested intervention. The registered 219 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (58% lower).
The record links to 0 conditions, and to 1 intervention - of which fluticasone is the first listed.
NCT00705341 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00705341 about?
NCT00705341 is a clinical study titled "MethaCholine Bronchoprovocation Study (MeCIS)". The purpose of this research is to evaluate the methacholine challenge test as an accurate indicator of asthma in patients receiving treatment for asthma. Phase 1 on the study compares methacholine challenge test results from asthma patients to those from people who do not have asthma. In phase 2, t...
What is the current status of trial NCT00705341?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 219 participants. The study started on 2009-01. Estimated completion is 2010-02.
What interventions are being tested in trial NCT00705341?
The interventions under investigation include: fluticasone (DRUG).
Who is sponsoring clinical trial NCT00705341?
This trial is sponsored by Johns Hopkins Bloomberg School of Public Health, which has 187 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00705341's enrollment target sits among peer trials
219 389th of 2000 higher than 1,611 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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