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NCT00698139 · ClinicalTrials.gov registry record · NA
Cardiovascular and Neurohormonal Effects of Faster Atrial Pacing Rate
A NA study, sponsored by Columbia University.
- Terminated
- Registry status
- NA
- Development phase
- 3
- Enrollment target
NCT00698139 is a NA study that was terminated before completion, run by Columbia University. The registered enrollment target is 3 participants.
The verdict
NCT00698139, a NA study, was terminated before completion, sponsored by Columbia University.
- TERMINATED
- Registry status
- NA
- Development phase
- 3 participants
- Enrollment target
Study Summary
Many patients with heart failure are unable to increase their heart rate appropriately when their body needs increased blood flow. As a result, they may be unable to mobilize excess fluid that their body retains. We hypothesize that we can provide assistance to their body in mobilizing this fluid by artificially increasing their heart rate using a pacemaker. We plan to conduct a prospective clinical trial to evaluate this hypothesis. We will use a cross over design to study patients who already have biventricular pacemakers implanted or a narrow QRS and volume overload. We will screen them using a blood test that is a rough estimate of volume overload. Patients who meet the inclusion criteria will be randomly assigned to have their pacemakers adjusted or to have no intervention during the first of 2 visits. They will be unaware of which group they are in. Following adjustment, they will be monitored for six hours. Prior to the pacemaker adjustment, several tests will be performed to evaluate heart function and the levels of hormones related that are affected by heart failure. These tests will be repeated at the end of the six hour intervention period in each visit. At the end of the visit patients who had their pacemakers adjusted will have it reset to their original settings.
Interventions
- DEVICE Medtronic Pacemaker
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2011-04 |
| Est. Completion | 2012-09 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00698139
The ClinicalTrials.gov registry entry for NCT00698139 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Medtronic Pacemaker is the first listed.
NCT00698139 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00698139 about?
NCT00698139 is a clinical study titled "Cardiovascular and Neurohormonal Effects of Faster Atrial Pacing Rate". Many patients with heart failure are unable to increase their heart rate appropriately when their body needs increased blood flow. As a result, they may be unable to mobilize excess fluid that their body retains. We hypothesize that we can provide assistance to their body in mobilizing this fluid by...
What is the current status of trial NCT00698139?
This trial is currently terminated. It is a NA study. The enrollment target is 3 participants. The study started on 2011-04. Estimated completion is 2012-09.
What interventions are being tested in trial NCT00698139?
The interventions under investigation include: Medtronic Pacemaker (DEVICE).
Who is sponsoring clinical trial NCT00698139?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
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