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NCT00697541 · ClinicalTrials.gov registry record · Phase 2

Systemic Bioavailability Study Of Col-118 Administered Topically as a 0.18 % Facial Gel And Brimonidine Ophthalmic Solution 0.2%

A Phase 2 study, sponsored by Galderma R&D.

Completed
Registry status
Phase 2
Development phase
20
Enrollment target

NCT00697541: Completed Phase 2 study, sponsored by Galderma R&D.

NCT00697541 is a Phase 2 study that has completed, run by Galderma R&D. The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00697541, a Phase 2 study, has completed, sponsored by Galderma R&D.

COMPLETED
Registry status
Phase 2
Development phase
20 participants
Enrollment target

Study Summary

Phase II systemic bioavailability crossover study to measure the exposure of Col-118 topical 0.18 % Facial Gel and Brimonidine Ophthalmic Solution 0.2%

Primary Outcome

Maximum observed plasma concentration

Interventions

  • DRUG 0.18% COL-118 facial gel (1.8 mg brimonidine)
  • DRUG 0.2% brimonidine ophthalmic solution (0.1 mg brimonidine tartrate/drop)
  • DRUG Advanced Eye Relief
  • DRUG COL-118 facial gel vehicle

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2008-05
Est. Completion 2008-06
Phase Phase 2
Galderma R&D

158 total trials

What the finished NCT00697541 record still lists

NCT00697541 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).

The record links to 0 conditions, and to 4 interventions - of which 0.18% COL-118 facial gel (1.8 mg brimonidine) is the first listed.

NCT00697541 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00697541 about?

NCT00697541 is a clinical study titled "Systemic Bioavailability Study Of Col-118 Administered Topically as a 0.18 % Facial Gel And Brimonidine Ophthalmic Solution 0.2%". Phase II systemic bioavailability crossover study to measure the exposure of Col-118 topical 0.18 % Facial Gel and Brimonidine Ophthalmic Solution 0.2%

What is the current status of trial NCT00697541?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2008-05. Estimated completion is 2008-06.

What interventions are being tested in trial NCT00697541?

The interventions under investigation include: 0.18% COL-118 facial gel (1.8 mg brimonidine) (DRUG), 0.2% brimonidine ophthalmic solution (0.1 mg brimonidine tartrate/drop) (DRUG), Advanced Eye Relief (DRUG), COL-118 facial gel vehicle (DRUG).

Who is sponsoring clinical trial NCT00697541?

This trial is sponsored by Galderma R&D, which has 158 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00697541's enrollment target sits among peer trials

20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00697541, the US trial registry maintained by the National Library of Medicine. NCT00697541 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.