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NCT00694655 · ClinicalTrials.gov registry record · Phase 4

Human Immune Responses to Yellow Fever Vaccination

A Phase 4 study, sponsored by Emory University.

Completed
Registry status
Phase 4
Development phase
239
Enrollment target

NCT00694655: Completed Phase 4 study, sponsored by Emory University.

NCT00694655 is a Phase 4 study that has completed, run by Emory University. The registered enrollment target is 239 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (54% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00694655, a Phase 4 study, has completed, sponsored by Emory University.

COMPLETED
Registry status
Phase 4
Development phase
239 participants
Enrollment target

Study Summary

The goal of this study is to use the live attenuated Yellow Fever Vaccine (YFV) as a safe and effective model for viral infection to understand human immune response to viral antigens. Study participants will receive the yellow fever vaccine and participation in the study may be as short as one month or as long as one year, depending on immune responses.

Primary Outcome

The characterization of Yellow Fever Vaccine specific adaptive immune response will be examined as the magnitude of YFV-specific T cell responses. The schedule of follow up visits depends on if participants test positive for human leukocyte antigen (HLA) A202 and the different immune system responses that the study team is examining at the time when each participant enrolls.

Interventions

  • PROCEDURE Leukapheresis
  • BIOLOGICAL Yellow Fever Vaccine
  • PROCEDURE Fine-needle aspiration (FNA)

Trial Details

FieldValue
Enrollment Target 239 participants
Start Date 2008-05
Est. Completion 2024-08-29
Phase Phase 4
Emory University

1,208 total trials

What the finished NCT00694655 record still lists

NCT00694655 is an interventional study that assigns participants to a tested intervention. The registered 239 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (54% lower).

The record links to 0 conditions, and to 3 interventions - of which Leukapheresis is the first listed.

NCT00694655 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00694655 about?

NCT00694655 is a clinical study titled "Human Immune Responses to Yellow Fever Vaccination". The goal of this study is to use the live attenuated Yellow Fever Vaccine (YFV) as a safe and effective model for viral infection to understand human immune response to viral antigens. Study participants will receive the yellow fever vaccine and participation in the study may be as short as one mont...

What is the current status of trial NCT00694655?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 239 participants. The study started on 2008-05. Estimated completion is 2024-08-29.

What interventions are being tested in trial NCT00694655?

The interventions under investigation include: Leukapheresis (PROCEDURE), Yellow Fever Vaccine (BIOLOGICAL), Fine-needle aspiration (FNA) (PROCEDURE).

Who is sponsoring clinical trial NCT00694655?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00694655's enrollment target sits among peer trials

239 366th of 2000 higher than 1,634 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00694655, the US trial registry maintained by the National Library of Medicine. NCT00694655 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.