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NCT00689819 · ClinicalTrials.gov registry record · NA
Pre-clinical Cardiac Dysfunction Among Asymptomatic Hypertensive Patients
A NA study, sponsored by Wayne State University.
- Completed
- Registry status
- NA
- Development phase
- 123
- Enrollment target
NCT00689819 is a NA study that has completed, run by Wayne State University. The registered enrollment target is 123 participants.
The verdict
NCT00689819, a NA study, has completed, sponsored by Wayne State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 123 participants
- Enrollment target
Study Summary
This project will evaluate the clinical and cost effectiveness of a novel, multidisciplinary approach to identify and treat pre-clinical cardiac dysfunction (PCCD) in asymptomatic hypertensive patients identified in a single center urban emergency department. Premature onset of pressure-related cardiac complications of hypertension (especially heart failure) has important implications for long-term survival, quality of life and healthcare costs. This project will target patients who have already developed pressure-related cardiac structural abnormalities yet remain symptom free. These individuals are at tremendous risk for progression to clinically overt heart failure and its associated consequences. We hypothesize that detection and treatment of patients with hypertension who have pre-clinical structural cardiac damage will enable forestallment of the disease process and offer the opportunity to reduce the burden of cardiac morbidity associated with hypertension. This project will implement a program to prospectively identify PCCD (using echocardiography) and provide treatment. At present, the optimal blood pressure goal for patients with PCCD is unknown so this study will randomize patients to 2 levels of blood pressure control: "normal", which is consistent with current national guidelines and "intensive", which will aim for a markedly lower blood pressure (\< 120/80). Enrolled patients will receive active treatment and follow-up for 1 year. At the end of 1 year, we will evaluate: 1) the ability of this program to achieve blood pressure goals; 2) the cost effectiveness; and 3) the proportion in each blood pressure group who have evidence of disease regression on echocardiography.
Interventions
- BEHAVIORAL Exercise
- BEHAVIORAL Smoking Cessation
- BEHAVIORAL Weight Loss
- BEHAVIORAL Low Sodium Diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 123 participants |
| Start Date | 2008-10 |
| Est. Completion | 2011-06 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00689819
The ClinicalTrials.gov registry entry for NCT00689819 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 123 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wayne State University, which has 163 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Exercise is the first listed.
NCT00689819 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00689819 about?
NCT00689819 is a clinical study titled "Pre-clinical Cardiac Dysfunction Among Asymptomatic Hypertensive Patients". This project will evaluate the clinical and cost effectiveness of a novel, multidisciplinary approach to identify and treat pre-clinical cardiac dysfunction (PCCD) in asymptomatic hypertensive patients identified in a single center urban emergency department. Premature onset of pressure-related card...
What is the current status of trial NCT00689819?
This trial is currently completed. It is a NA study. The enrollment target is 123 participants. The study started on 2008-10. Estimated completion is 2011-06.
What interventions are being tested in trial NCT00689819?
The interventions under investigation include: Exercise (BEHAVIORAL), Smoking Cessation (BEHAVIORAL), Weight Loss (BEHAVIORAL), Low Sodium Diet (BEHAVIORAL).
Who is sponsoring clinical trial NCT00689819?
This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.
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