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NCT00689754 · ClinicalTrials.gov registry record · NA

Efficacy and Safety Study on Nasogastric (NG) Tube in Patients With Upper Gastrointestinal Bleed

A NA study of Liver Cirrhosis and Gastrointestinal Hemorrhage, sponsored by University of Texas Southwestern Medical Center.

Completed
Registry status
NA
Development phase
282
Enrollment target
1
Study location

NCT00689754 is a NA study of Liver Cirrhosis and Gastrointestinal Hemorrhage that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 282 participants, below the 986-participant average among 15 other Liver Cirrhosis trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00689754, a NA study of Liver Cirrhosis and Gastrointestinal Hemorrhage, has completed, sponsored by University of Texas Southwestern Medical Center.

COMPLETED
Registry status
NA
Development phase
282 participants
Enrollment target
1
Study location

Study Summary

Upper gastrointestinal tract hemorrhage (UGIH) remains a major cause of morbidity and mortality . Nasogastric aspiration (NGA) is routinely performed in patients with UGIH to obtain important clinical data and make therapeutic decisions. But routine use of NGA remains controversial with studies reporting its usefulness and its redundant clinical information. Early esophagogastroduodenoscopy (EGD) is recommended by most gastrointestinal societies to allow for risk stratification and to perform endoscopic treatments. The results of the NGA may assist to differentiate between high-risk versus low-risk lesions. Our hypothesis is that presence of NGA can identify lesions that require endoscopic treatment and provides important clinical information to guide the treating physician. In addition, we hypothesized that the results of the NGA influence the clinical decision of the treating physician regarding the prediction of the need for endoscopic therapy. This observational randomized cross-sectional study will enroll consecutive patients with presumed UGIH and randomized them to NGA and no NGA recording its results. All patients will receive an EGD and its results will also be recorded. Subsequently, we will evaluate if the NGA is important in identifying endoscopically significant lesions. The information gained will help guide clinicians evaluating patient with UGIH.

Interventions

  • PROCEDURE nasogastric tube placement

Study Locations (1)

Texas

  • Parkland Memorial Hospital - Dallas

Trial Details

FieldValue
Enrollment Target 282 participants
Start Date 2008-01
Est. Completion 2011-08
Phase NA

What the Registry Record Tells You About NCT00689754

The ClinicalTrials.gov registry entry for NCT00689754 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 282 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 986-participant average among 15 other Liver Cirrhosis trials with a reported enrollment target (71% lower). The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Liver Cirrhosis appearing as the primary indexed condition, and to 1 intervention - of which nasogastric tube placement is the first listed.

NCT00689754 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT00689754 about?

NCT00689754 is a clinical study titled "Efficacy and Safety Study on Nasogastric (NG) Tube in Patients With Upper Gastrointestinal Bleed". Upper gastrointestinal tract hemorrhage (UGIH) remains a major cause of morbidity and mortality . Nasogastric aspiration (NGA) is routinely performed in patients with UGIH to obtain important clinical data and make therapeutic decisions. But routine use of NGA remains controversial with studies repo...

What is the current status of trial NCT00689754?

This trial is currently completed. It is a NA study. The enrollment target is 282 participants. The study started on 2008-01. Estimated completion is 2011-08.

What conditions does trial NCT00689754 study?

This clinical trial studies the following conditions: Liver Cirrhosis, Gastrointestinal Hemorrhage.

What interventions are being tested in trial NCT00689754?

The interventions under investigation include: nasogastric tube placement (PROCEDURE).

Who is sponsoring clinical trial NCT00689754?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00689754 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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