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NCT00686231 · ClinicalTrials.gov registry record · Phase 1
Radial Artery Dilation Study: The Effect of Topical Administration of Nitroglycerin and Lidocaine Versus Lidocaine Alone of the Radial Artery Diameter
A Phase 1 study, sponsored by University of California, San Francisco.
- Completed
- Registry status
- Phase 1
- Development phase
- 19
- Enrollment target
NCT00686231: Completed Phase 1 study, sponsored by University of California, San Francisco.
NCT00686231 is a Phase 1 study that has completed, run by University of California, San Francisco. The registered enrollment target is 19 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00686231, a Phase 1 study, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 19 participants
- Enrollment target
Study Summary
The radial artery, which is located on the outer side of the forearm, can be used in interventional procedures, such as cardiac catheterization, to provide access to the arterial blood supply. In order to facilitate successful catheterization of the artery, a dilated artery and one free of arterial spasm is desirable. The proposed study will randomize twenty three healthy subjects in 2 visits to determine the effect of topical nitroglycerin on radial artery vasodilation. Radial artery diameter will be measured with ultrasound at regular intervals up to two hours.
Primary Outcome
Radial artery diameter was measured with ultrasonography using a high-frequency (13 MHz) linear array transducer 2 cm proximal to the radial styloid process.
Interventions
- DRUG Placebo
- DRUG Nitroglycerin 15mg
- DRUG Nitroglycerin 30mg
- DRUG Lidocaine 20mg
- DRUG Lidocaine 40mg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2008-05 |
| Est. Completion | 2008-12 |
| Phase | Phase 1 |
What the finished NCT00686231 record still lists
NCT00686231 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 5 interventions - of which Placebo is the first listed.
NCT00686231 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00686231 about?
NCT00686231 is a clinical study titled "Radial Artery Dilation Study: The Effect of Topical Administration of Nitroglycerin and Lidocaine Versus Lidocaine Alone of the Radial Artery Diameter". The radial artery, which is located on the outer side of the forearm, can be used in interventional procedures, such as cardiac catheterization, to provide access to the arterial blood supply. In order to facilitate successful catheterization of the artery, a dilated artery and one free of arterial ...
What is the current status of trial NCT00686231?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2008-05. Estimated completion is 2008-12.
What interventions are being tested in trial NCT00686231?
The interventions under investigation include: Placebo (DRUG), Nitroglycerin 15mg (DRUG), Nitroglycerin 30mg (DRUG), Lidocaine 20mg (DRUG), Lidocaine 40mg (DRUG).
Who is sponsoring clinical trial NCT00686231?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00686231's enrollment target sits among peer trials
19 1716th of 2000 higher than 281 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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