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NCT00685919 · ClinicalTrials.gov registry record · Phase 2

Peripheral Dopamine in Postural Tachycardia Syndrome

A Phase 2 study, sponsored by Vanderbilt University.

Completed
Registry status
Phase 2
Development phase
32
Enrollment target

NCT00685919 is a Phase 2 study that has completed, run by Vanderbilt University. The registered enrollment target is 32 participants.

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The verdict

NCT00685919, a Phase 2 study, has completed, sponsored by Vanderbilt University.

COMPLETED
Registry status
Phase 2
Development phase
32 participants
Enrollment target

Study Summary

The purpose of the proposed research is to determine how changes in kidney dopamine (DA) activity influence urinary sodium excretion. We will decrease DA activity in the kidney by inhibiting DA synthesis via carbidopa administration. We want to compare findings in normal volunteers and in patients with postural tachycardia syndrome (POTS). We will test the null hypothesis (Ho) that the effects of oral carbidopa administration on urinary sodium excretion will not differ between patients with POTS and healthy volunteers.

Interventions

  • DRUG Placebo
  • DRUG Carbidopa

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2008-05
Est. Completion 2021-12
Phase Phase 2

Sponsor

Vanderbilt University

430 total trials

What the Registry Record Tells You About NCT00685919

The ClinicalTrials.gov registry entry for NCT00685919 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University, which has 430 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00685919 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00685919 about?

NCT00685919 is a clinical study titled "Peripheral Dopamine in Postural Tachycardia Syndrome". The purpose of the proposed research is to determine how changes in kidney dopamine (DA) activity influence urinary sodium excretion. We will decrease DA activity in the kidney by inhibiting DA synthesis via carbidopa administration. We want to compare findings in normal volunteers and in patients w...

What is the current status of trial NCT00685919?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 32 participants. The study started on 2008-05. Estimated completion is 2021-12.

What interventions are being tested in trial NCT00685919?

The interventions under investigation include: Placebo (DRUG), Carbidopa (DRUG).

Who is sponsoring clinical trial NCT00685919?

This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.