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NCT00685230 · ClinicalTrials.gov registry record · Phase 2

Double-Blind, Alacramyn® vs. Placebo in Pediatric Patients

A Phase 2 study, sponsored by Instituto Bioclon S.A. de C.V..

Completed
Registry status
Phase 2
Development phase
15
Enrollment target

NCT00685230 is a Phase 2 study that has completed, run by Instituto Bioclon S.A. de C.V.. The registered enrollment target is 15 participants.

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The verdict

NCT00685230, a Phase 2 study, has completed, sponsored by Instituto Bioclon S.A. de C.V..

COMPLETED
Registry status
Phase 2
Development phase
15 participants
Enrollment target

Study Summary

There is no FDA approved therapy for the treatment of scorpion envenomation, Centruroides scorpion envenomation produces a pattern of neurotoxicity with a spectrum of severity ranging from trivial to life threatening. Patients stung by Centruroides scorpions develop a clinical syndrome which may require sedation with benzodiazepines and observation for 6 to 28 hours of intensive care monitoring. A safe therapy is necessary to halt the progression of symptoms early in the clinical course while avoiding the clinical deterioration that can occur en route to a tertiary facility. Alacramyn® is anticipated to be safer and more effective than the present standard of care, midazolam, and faster-acting such that the need for transport of most rural patients will be eliminated and will reduce hospitalization time. The working hypotheses are as follows: 1. The investigational antivenom is safe as treatment of scorpion sting envenomation. 2. The investigational antivenom is effective as treatment of scorpion sting envenomation.

Interventions

  • OTHER Placebo
  • BIOLOGICAL Antivenin Centruroides (scorpion) equine immune F(ab)2

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2004-05
Est. Completion 2005-10
Phase Phase 2

Sponsor

Instituto Bioclon S.A. de C.V.

8 total trials

What the Registry Record Tells You About NCT00685230

The ClinicalTrials.gov registry entry for NCT00685230 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Instituto Bioclon S.A. de C.V., which has 8 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00685230 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00685230 about?

NCT00685230 is a clinical study titled "Double-Blind, Alacramyn® vs. Placebo in Pediatric Patients". There is no FDA approved therapy for the treatment of scorpion envenomation, Centruroides scorpion envenomation produces a pattern of neurotoxicity with a spectrum of severity ranging from trivial to life threatening. Patients stung by Centruroides scorpions develop a clinical syndrome which may req...

What is the current status of trial NCT00685230?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2004-05. Estimated completion is 2005-10.

What interventions are being tested in trial NCT00685230?

The interventions under investigation include: Placebo (OTHER), Antivenin Centruroides (scorpion) equine immune F(ab)2 (BIOLOGICAL).

Who is sponsoring clinical trial NCT00685230?

This trial is sponsored by Instituto Bioclon S.A. de C.V., which has 8 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.