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NCT00684060 · ClinicalTrials.gov registry record · Phase 2

Use of Adult Autologous Stem Cells in Treating People 2 to 3 Weeks After Having a Heart Attack (The Late TIME Study)

A Phase 2 study, sponsored by The University of Texas Health Science Center, Houston.

Completed
Registry status
Phase 2
Development phase
87
Enrollment target

NCT00684060: Completed Phase 2 study, sponsored by The University of Texas Health Science Center, Houston.

NCT00684060 is a Phase 2 study that has completed, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 87 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (35% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00684060, a Phase 2 study, has completed, sponsored by The University of Texas Health Science Center, Houston.

COMPLETED
Registry status
Phase 2
Development phase
87 participants
Enrollment target

Study Summary

More than 1 million Americans suffer heart attacks each year. Although current treatments are able to stabilize the condition of the heart, none is able to restore heart function as it was prior to the heart attack. Adult stem cells, which are immature cells that can become many different types of cells, may offer a potential means of reversing or preventing permanent damage caused by a heart attack. Recent studies have shown promise in using adult stem cells from bone marrow to reverse damage to the heart muscle caused by a heart attack, but more research is needed to assess the safety and effectiveness of stem cell use and to discover the best time to administer treatment. This study will evaluate the safety and effectiveness of using adult stem cell infusions 2 to 3 weeks after a heart attack for improving heart function in people who have had a recent heart attack and a common procedure called a percutaneous coronary intervention (PCI).

Primary Outcome

Left ventricular ejection fraction (global) as assessed via cardiac MRI. Values reported represent the change in Global EF from baseline to six months.

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL Adult stem cells

Trial Details

FieldValue
Enrollment Target 87 participants
Start Date 2008-07
Est. Completion 2012-02
Phase Phase 2

What the finished NCT00684060 record still lists

NCT00684060 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 87 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (35% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00684060 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00684060 about?

NCT00684060 is a clinical study titled "Use of Adult Autologous Stem Cells in Treating People 2 to 3 Weeks After Having a Heart Attack (The Late TIME Study)". More than 1 million Americans suffer heart attacks each year. Although current treatments are able to stabilize the condition of the heart, none is able to restore heart function as it was prior to the heart attack. Adult stem cells, which are immature cells that can become many different types of c...

What is the current status of trial NCT00684060?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 87 participants. The study started on 2008-07. Estimated completion is 2012-02.

What interventions are being tested in trial NCT00684060?

The interventions under investigation include: Placebo (BIOLOGICAL), Adult stem cells (BIOLOGICAL).

Who is sponsoring clinical trial NCT00684060?

This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00684060's enrollment target sits among peer trials

87 810th of 2000 higher than 1,189 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00684060, the US trial registry maintained by the National Library of Medicine. NCT00684060 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.