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NCT00683787 · ClinicalTrials.gov registry record · Phase 2

Docetaxel With or Without Vandetanib in Treating Patients With Metastatic Stomach Cancer or Gastroesophageal Junction Cancer

A Phase 2 study, sponsored by Roswell Park Cancer Institute.

Terminated
Registry status
Phase 2
Development phase
8
Enrollment target

NCT00683787: Clinical Trial Phase 2 study, sponsored by Roswell Park Cancer Institute.

NCT00683787 is a Phase 2 study that was terminated before completion, run by Roswell Park Cancer Institute. The registered enrollment target is 8 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00683787, a Phase 2 study, was terminated before completion, sponsored by Roswell Park Cancer Institute.

TERMINATED
Registry status
Phase 2
Development phase
8 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Vandetanib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. It is not yet known whether docetaxel is more effective when given together with or without vandetanib. PURPOSE: This randomized phase II trial is studying docetaxel to see how well it works compared with docetaxel given together with vandetanib in treating patients with metastatic stomach cancer or gastroesophageal junction cancer.

Interventions

  • DRUG docetaxel
  • DRUG vandetanib

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2008-05
Est. Completion 2011-03
Phase Phase 2
Roswell Park Cancer Institute

365 total trials

Why NCT00683787 stopped before completion

NCT00683787 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 2 interventions - of which docetaxel is the first listed.

NCT00683787 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00683787 about?

NCT00683787 is a clinical study titled "Docetaxel With or Without Vandetanib in Treating Patients With Metastatic Stomach Cancer or Gastroesophageal Junction Cancer". RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Vandetanib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking bloo...

What is the current status of trial NCT00683787?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2008-05. Estimated completion is 2011-03.

What interventions are being tested in trial NCT00683787?

The interventions under investigation include: docetaxel (DRUG), vandetanib (DRUG).

Who is sponsoring clinical trial NCT00683787?

This trial is sponsored by Roswell Park Cancer Institute, which has 365 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00683787's enrollment target sits among peer trials

8 1990th of 2000 higher than 5 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00683787, the US trial registry maintained by the National Library of Medicine. NCT00683787 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.