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NCT00683696 · ClinicalTrials.gov registry record · Phase 2

Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT)

A Phase 2 study, sponsored by Biotronik.

Terminated
Registry status
Phase 2
Development phase
1,680
Enrollment target

NCT00683696: Clinical Trial Phase 2 study, sponsored by Biotronik.

NCT00683696 is a Phase 2 study that was terminated before completion, run by Biotronik. The registered enrollment target is 1,680 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (1163% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00683696, a Phase 2 study, was terminated before completion, sponsored by Biotronik.

TERMINATED
Registry status
Phase 2
Development phase
1,680 participants
Enrollment target

Study Summary

The EchoCRT trial evaluates the effects of Cardiac Resynchronization Therapy (CRT) on mortality and morbidity of subjects with heart failure due to left ventricular systolic dysfunction, already receiving optimized HF medication, with a narrow QRS width (\< 130 ms) and echocardiographic evidence of ventricular dyssynchrony.

Primary Outcome

The primary efficacy endpoint will evaluate the effect of CRT=ON versus CRT=OFF in time to event of a combined endpoint of all-cause mortality or first hospitalization for worsening heart failure.

Interventions

  • DEVICE Implantable Cardioverter Defibrillator with Cardiac Resynchronization Therapy (BIOTRONIK Lumax HF-T CRT-D)

Trial Details

FieldValue
Enrollment Target 1,680 participants
Start Date 2008-08
Est. Completion 2013-03
Phase Phase 2
Biotronik

30 total trials

Why NCT00683696 stopped before completion

NCT00683696 is an interventional study that assigns participants to a tested intervention. Its 1,680 participants enrollment target places it among the larger protocols in the corpus, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (1163% higher).

The record links to 0 conditions, and to 1 intervention - of which Implantable Cardioverter Defibrillator with Cardiac Resynchronization Therapy (BIOTRONIK Lumax HF-T CRT-D) is the first listed.

NCT00683696 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00683696 about?

NCT00683696 is a clinical study titled "Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT)". The EchoCRT trial evaluates the effects of Cardiac Resynchronization Therapy (CRT) on mortality and morbidity of subjects with heart failure due to left ventricular systolic dysfunction, already receiving optimized HF medication, with a narrow QRS width (\< 130 ms) and echocardiographic evidence of ...

What is the current status of trial NCT00683696?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 1,680 participants. The study started on 2008-08. Estimated completion is 2013-03.

What interventions are being tested in trial NCT00683696?

The interventions under investigation include: Implantable Cardioverter Defibrillator with Cardiac Resynchronization Therapy (BIOTRONIK Lumax HF-T CRT-D) (DEVICE).

Who is sponsoring clinical trial NCT00683696?

This trial is sponsored by Biotronik, which has 30 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00683696's enrollment target sits among peer trials

1,680 11th of 2000 higher than 1,990 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00683696, the US trial registry maintained by the National Library of Medicine. NCT00683696 (large enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.