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NCT00679991 · ClinicalTrials.gov registry record · Phase 1

A Phase 1-2 Study of PRT-201 Administered in Chronic Kidney Disease (CKD) Patients

A Phase 1 study, sponsored by Proteon Therapeutics.

Completed
Registry status
Phase 1
Development phase
66
Enrollment target

NCT00679991: Completed Phase 1 study, sponsored by Proteon Therapeutics.

NCT00679991 is a Phase 1 study that has completed, run by Proteon Therapeutics. The registered enrollment target is 66 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00679991, a Phase 1 study, has completed, sponsored by Proteon Therapeutics.

COMPLETED
Registry status
Phase 1
Development phase
66 participants
Enrollment target

Study Summary

PRT-201 is a protein that causes long lasting dilation of blood vessels when applied to the outside surface of the blood vessel. The purpose of this study is to determine if PRT-201, when applied to a limited segment of blood vessel immediately after surgery to create an arteriovenous fistula (AVF), is safe, dilates the blood vessel, and increases blood flow through the AVF.

Interventions

  • DRUG PRT-201

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2008-11
Est. Completion 2011-07
Phase Phase 1
Proteon Therapeutics

7 total trials

What the finished NCT00679991 record still lists

NCT00679991 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% higher).

The record links to 0 conditions, and to 1 intervention - of which PRT-201 is the first listed.

NCT00679991 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00679991 about?

NCT00679991 is a clinical study titled "A Phase 1-2 Study of PRT-201 Administered in Chronic Kidney Disease (CKD) Patients". PRT-201 is a protein that causes long lasting dilation of blood vessels when applied to the outside surface of the blood vessel. The purpose of this study is to determine if PRT-201, when applied to a limited segment of blood vessel immediately after surgery to create an arteriovenous fistula (AVF),...

What is the current status of trial NCT00679991?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 66 participants. The study started on 2008-11. Estimated completion is 2011-07.

What interventions are being tested in trial NCT00679991?

The interventions under investigation include: PRT-201 (DRUG).

Who is sponsoring clinical trial NCT00679991?

This trial is sponsored by Proteon Therapeutics, which has 7 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00679991's enrollment target sits among peer trials

66 786th of 2000 higher than 1,203 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00679991, the US trial registry maintained by the National Library of Medicine. NCT00679991 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.