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NCT00676026 · ClinicalTrials.gov registry record · NA
Impact of GABA-Enhancing Agents on Cortical GABA Concentrations Across the Menstrual Cycle in Women
A NA study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- NA
- Development phase
- 8
- Enrollment target
NCT00676026: Completed NA study, sponsored by University of Pennsylvania.
NCT00676026 is a NA study that has completed, run by University of Pennsylvania. The registered enrollment target is 8 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00676026, a NA study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- NA
- Development phase
- 8 participants
- Enrollment target
Study Summary
The goal of this series of challenge studies is to examine the impact of menstrual cycle phase on cortical GABA response to administration of agents with either direct (benzodiazepines) or indirect (progesterone, fluoxetine) GABA modulating properties. While the impact of these agents on cortical GABA levels in women with premenstrual dysphoric disorder (PMDD) is of interest, this study is designed primarily for those women without a psychiatric illness.
Primary Outcome
This study was conducted at Yale University almost two decades ago. Our group at the University of Pennsylvania only has very basic information about this study. This includes the number of participants, which was 8, and the fact that no adverse events occurred. Staff members at the University of Pennsylvania do not have access to any additional study data. The contact person who initially entered this study protocol information is no longer at the University of Pennsylvania and we are unable to
Interventions
- DRUG Progesterone
- DRUG Zolpidem
- DRUG Fluoxetine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2005-05 |
| Est. Completion | 2009-02 |
| Phase | NA |
What the finished NCT00676026 record still lists
NCT00676026 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 3 interventions - of which Progesterone is the first listed.
NCT00676026 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00676026 about?
NCT00676026 is a clinical study titled "Impact of GABA-Enhancing Agents on Cortical GABA Concentrations Across the Menstrual Cycle in Women". The goal of this series of challenge studies is to examine the impact of menstrual cycle phase on cortical GABA response to administration of agents with either direct (benzodiazepines) or indirect (progesterone, fluoxetine) GABA modulating properties. While the impact of these agents on cortical GA...
What is the current status of trial NCT00676026?
This trial is currently completed. It is a NA study. The enrollment target is 8 participants. The study started on 2005-05. Estimated completion is 2009-02.
What interventions are being tested in trial NCT00676026?
The interventions under investigation include: Progesterone (DRUG), Zolpidem (DRUG), Fluoxetine (DRUG).
Who is sponsoring clinical trial NCT00676026?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00676026's enrollment target sits among peer trials
8 1976th of 2000 higher than 19 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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