Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00672737 · ClinicalTrials.gov registry record
Study of Pain Processing in Subjects Suffering From Obstructive Sleep Apnea
A clinical trial, sponsored by Stanford University.
- Completed
- Registry status
- 56
- Enrollment target
NCT00672737: Completed study, sponsored by Stanford University.
NCT00672737 is a clinical trial that has completed, run by Stanford University. The registered enrollment target is 56 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00672737 has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- 56 participants
- Enrollment target
Study Summary
We would like to test the effect of opioid medication on pain sensitivity in subjects who have been diagnosed with a sleep disorder called Obstructive Sleep Apnea (OSA) compared to other subjects without OSA. Patients with OSA may have an altered sensitivity to the sedative, analgesic, and respiratory depressant effects of opioids.
Primary Outcome
The effect of insulin growth factor binding protein-1 (IGFBP-1), a serum hypoxia marker, on the change of cold-induced pain thresholds under remifentanil was estimated using a mixed linear regression model. The results were expressed by the estimated beta (95% CI), indicating how much the change in the cold pain threshold (expressed in seconds) under remifentanil, was altered per unit of change in the IGFBP-1. For example, for every 1-pg/mL increase in the serum level of IGFBP-1, cold pain thres
Interventions
- DRUG Remifentanil
- PROCEDURE Polysomnography
- PROCEDURE Cold pain threshold and tolerance
- DEVICE Heat pain threshold and tolerance
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2008-02 |
| Est. Completion | 2010-08 |
What the finished NCT00672737 record still lists
NCT00672737 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 56 participants, a relatively small participant target.
The record links to 0 conditions, and to 4 interventions - of which Remifentanil is the first listed.
NCT00672737 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00672737 about?
NCT00672737 is a clinical study titled "Study of Pain Processing in Subjects Suffering From Obstructive Sleep Apnea". We would like to test the effect of opioid medication on pain sensitivity in subjects who have been diagnosed with a sleep disorder called Obstructive Sleep Apnea (OSA) compared to other subjects without OSA. Patients with OSA may have an altered sensitivity to the sedative, analgesic, and respirato...
What is the current status of trial NCT00672737?
This trial is currently completed. The enrollment target is 56 participants. The study started on 2008-02. Estimated completion is 2010-08.
What interventions are being tested in trial NCT00672737?
The interventions under investigation include: Remifentanil (DRUG), Polysomnography (PROCEDURE), Cold pain threshold and tolerance (PROCEDURE), Heat pain threshold and tolerance (DEVICE).
Who is sponsoring clinical trial NCT00672737?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02287428 · 56 participants · Phase 1
Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM
- NCT02923011 · 56 participants · Phase 3
Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas
- NCT02935283 · 56 participants
Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders
- NCT03375866 · 56 participants · NA
Effects of Mixed Nut Consumption on Satiety and Weight Management
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia