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NCT00671593 · ClinicalTrials.gov registry record · Phase 1

Differential Gene Expression in Lung and Peripheral Blood After Inhaled Allergen Challenge

A Phase 1 study, sponsored by John Sundy.

Terminated
Registry status
Phase 1
Development phase
40
Enrollment target

NCT00671593: Clinical Trial Phase 1 study, sponsored by John Sundy.

NCT00671593 is a Phase 1 study that was terminated before completion, run by John Sundy. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00671593, a Phase 1 study, was terminated before completion, sponsored by John Sundy.

TERMINATED
Registry status
Phase 1
Development phase
40 participants
Enrollment target

Study Summary

The purpose of this study is to identify the genes in important airway cells that are specifically expressed following inhalation of house dust mite allergen among study subjects with either allergic asthma or healthy normal phenotypes. This approach is designed to identify novel genes associated with both asthma pathogenesis (differentially expressed in the exposure-response study) and asthma susceptibility (genetically associated with asthma in a linkage/association study) for drug targets.

Interventions

  • BIOLOGICAL Diluent
  • BIOLOGICAL House Dust Mite

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2006-10
Est. Completion 2009-04
Phase Phase 1
John Sundy

6 total trials

Why NCT00671593 stopped before completion

NCT00671593 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).

The record links to 0 conditions, and to 2 interventions - of which Diluent is the first listed.

NCT00671593 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00671593 about?

NCT00671593 is a clinical study titled "Differential Gene Expression in Lung and Peripheral Blood After Inhaled Allergen Challenge". The purpose of this study is to identify the genes in important airway cells that are specifically expressed following inhalation of house dust mite allergen among study subjects with either allergic asthma or healthy normal phenotypes. This approach is designed to identify novel genes associated wi...

What is the current status of trial NCT00671593?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2006-10. Estimated completion is 2009-04.

What interventions are being tested in trial NCT00671593?

The interventions under investigation include: Diluent (BIOLOGICAL), House Dust Mite (BIOLOGICAL).

Who is sponsoring clinical trial NCT00671593?

This trial is sponsored by John Sundy, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00671593's enrollment target sits among peer trials

40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00671593, the US trial registry maintained by the National Library of Medicine. NCT00671593 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.