Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Escitalopram in Adult Patients With Major Depressive Disorder
NCT00668525 · View on ClinicalTrials.gov ↗
Study Summary
This is a short-term study to evaluate the efficacy, safety, and tolerability of escitalopram in adult patients (18 to 65 years of age) with moderate to severe depression. Patients completing the study may be eligible to enter a long-term open-label extension study with escitalopram.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Escitalopram
Study Locations (20)
California
- Forest Investigative Site — Arcadia
- Forest Investigative Site — Encino
- Forest Investigative Site — Garden Grove
- Forest Investigative Site — Irvine
- Forest Investigative Site — Los Alamitos
Florida
- Forest Investigative Site — Bradenton
- Forest Investigative Site — Jacksonville
- Forest Investigative Site — Orlando
- Forest Investigative Site — West Palm Beach
Maryland
- Forest Investigative Site — Baltimore
- Forest Investigative Site — Glen Burnie
- Forest Investigative Site — Rockville
Kansas
- Forest Investigative Site — Newton
- Forest Investigative Site — Overland
Arizona
- Forest Investigative Site — Phoenix
Colorado
- Forest Investigative Site — Denver
District of Columbia
- Forest Investigative Site — Washington D.C.
Georgia
- Forest Investigative Site — Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 877 participants |
| Start Date | 2008-04 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00668525
The ClinicalTrials.gov registry entry for NCT00668525 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 877 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Forest Laboratories, which has 32 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Major Depressive Disorder appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00668525 reports 20 study locations spanning 10 distinct geographic areas — top geographies include California, Florida, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00668525 about?
NCT00668525 is a clinical study titled "Escitalopram in Adult Patients With Major Depressive Disorder". This is a short-term study to evaluate the efficacy, safety, and tolerability of escitalopram in adult patients (18 to 65 years of age) with moderate to severe depression. Patients completing the study may be eligible to enter a long-term open-label extension study with escitalopram.
What is the current status of trial NCT00668525?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 877 participants. The study started on 2008-04.
What conditions does trial NCT00668525 study?
This clinical trial studies the following conditions: Major Depressive Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00668525?
The interventions under investigation include: Placebo (DRUG), Escitalopram (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00668525?
This trial is sponsored by Forest Laboratories, which has 32 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00668525 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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