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NCT00667901 · ClinicalTrials.gov registry record · Phase 1

Riluzole in Treating Patients With Stage III or Stage IV Melanoma That Can Be Removed by Surgery

A Phase 1 study, sponsored by University of Medicine and Dentistry of New Jersey.

Terminated
Registry status
Phase 1
Development phase
15
Enrollment target

NCT00667901: Clinical Trial Phase 1 study, sponsored by University of Medicine and Dentistry of New Jersey.

NCT00667901 is a Phase 1 study that was terminated before completion, run by University of Medicine and Dentistry of New Jersey. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00667901, a Phase 1 study, was terminated before completion, sponsored by University of Medicine and Dentistry of New Jersey.

TERMINATED
Registry status
Phase 1
Development phase
15 participants
Enrollment target

Study Summary

RATIONALE: Riluzole may stop or slow the growth of tumor cells and may be an effective treatment for melanoma. PURPOSE: This early phase I trial is studying how well riluzole works in treating patients with stage III or stage IV melanoma that can be removed by surgery.

Interventions

  • GENETIC protein expression analysis
  • OTHER immunohistochemistry staining method
  • GENETIC western blotting
  • GENETIC reverse transcriptase-polymerase chain reaction
  • DRUG riluzole

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2007-02
Est. Completion 2008-11
Phase Phase 1

Why NCT00667901 stopped before completion

NCT00667901 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).

The record links to 0 conditions, and to 5 interventions - of which protein expression analysis is the first listed.

NCT00667901 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00667901 about?

NCT00667901 is a clinical study titled "Riluzole in Treating Patients With Stage III or Stage IV Melanoma That Can Be Removed by Surgery". RATIONALE: Riluzole may stop or slow the growth of tumor cells and may be an effective treatment for melanoma. PURPOSE: This early phase I trial is studying how well riluzole works in treating patients with stage III or stage IV melanoma that can be removed by surgery.

What is the current status of trial NCT00667901?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2007-02. Estimated completion is 2008-11.

What interventions are being tested in trial NCT00667901?

The interventions under investigation include: protein expression analysis (GENETIC), immunohistochemistry staining method (OTHER), western blotting (GENETIC), reverse transcriptase-polymerase chain reaction (GENETIC), riluzole (DRUG).

Who is sponsoring clinical trial NCT00667901?

This trial is sponsored by University of Medicine and Dentistry of New Jersey, which has 88 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00667901's enrollment target sits among peer trials

15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00667901, the US trial registry maintained by the National Library of Medicine. NCT00667901 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.