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NCT00667810 · ClinicalTrials.gov registry record · Phase 3

Study Evaluating The Efficacy And Safety Of Bapineuzumab In Alzheimer Disease Patients

A Phase 3 study, sponsored by Pfizer.

Terminated
Registry status
Phase 3
Development phase
901
Enrollment target

NCT00667810: Clinical Trial Phase 3 study, sponsored by Pfizer.

NCT00667810 is a Phase 3 study that was terminated before completion, run by Pfizer. The registered enrollment target is 901 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (17% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00667810, a Phase 3 study, was terminated before completion, sponsored by Pfizer.

TERMINATED
Registry status
Phase 3
Development phase
901 participants
Enrollment target

Study Summary

This is a study to evaluate the efficacy and safety of multiple doses of bapineuzumab in patients with mild to moderate Alzheimer Disease. Patients will receive either bapineuzumab or placebo. Each patient's participation will last approximately 1.5 years.

Primary Outcome

The ADAS-Cog is a multi-item, objective measure of cognitive function. The scale evaluates memory, language, and praxis with items such as orientation, word recall, word recognition, object identification, comprehension, and the completion of simple tasks. Analysis of the ADAS-Cog for this study was based upon an 11 item score from the following items 1) word recall task, 2) naming objects and fingers, 3) following commands, 4) constructional praxis, 5) ideational praxis, 6) orientation, 7) word

Interventions

  • DRUG placebo
  • DRUG bapineuzumab

Trial Details

FieldValue
Enrollment Target 901 participants
Start Date 2008-06
Est. Completion 2013-08
Phase Phase 3
Pfizer

1,845 total trials

Why NCT00667810 stopped before completion

NCT00667810 is an interventional study that assigns participants to a tested intervention. The registered 901 participants enrollment target is mid-sized for trials with a published cap, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (17% higher).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT00667810 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00667810 about?

NCT00667810 is a clinical study titled "Study Evaluating The Efficacy And Safety Of Bapineuzumab In Alzheimer Disease Patients". This is a study to evaluate the efficacy and safety of multiple doses of bapineuzumab in patients with mild to moderate Alzheimer Disease. Patients will receive either bapineuzumab or placebo. Each patient's participation will last approximately 1.5 years.

What is the current status of trial NCT00667810?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 901 participants. The study started on 2008-06. Estimated completion is 2013-08.

What interventions are being tested in trial NCT00667810?

The interventions under investigation include: placebo (DRUG), bapineuzumab (DRUG).

Who is sponsoring clinical trial NCT00667810?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00667810's enrollment target sits among peer trials

901 349th of 2000 higher than 1,651 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00667810, the US trial registry maintained by the National Library of Medicine. NCT00667810 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.