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NCT00660660 · ClinicalTrials.gov registry record · Phase 4
Local Phase IV, Gastroesophageal Reflux Disease (GERD) Sleep Study US
A Phase 4 study, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 4
- Development phase
- 276
- Enrollment target
NCT00660660: Completed Phase 4 study, sponsored by AstraZeneca.
NCT00660660 is a Phase 4 study that has completed, run by AstraZeneca. The registered enrollment target is 276 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00660660, a Phase 4 study, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 276 participants
- Enrollment target
Study Summary
The purpose of this research study is to compare the safety and effectiveness (how well the medicine works) of esomeprazole (study drug) to placebo (a capsule that does not contain any medication) taken daily in relieving nighttime heartburn and problems sleeping in patients with gastroesophageal reflux disease (GERD).
Primary Outcome
Relief of nighttime heartburn on patient's last 7 days in the study. Relief was defined as a daily diary card response of "none" or 0, on at least 6 of 7 days, allowing for one "mild" or 1 response. Diary card scale (none, mild, moderate, severe).
Interventions
- DRUG Placebo
- DRUG Esomeprazole
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 276 participants |
| Start Date | 2008-04 |
| Est. Completion | 2008-07 |
| Phase | Phase 4 |
What the finished NCT00660660 record still lists
NCT00660660 is an interventional study that assigns participants to a tested intervention. The registered 276 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (47% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00660660 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00660660 about?
NCT00660660 is a clinical study titled "Local Phase IV, Gastroesophageal Reflux Disease (GERD) Sleep Study US". The purpose of this research study is to compare the safety and effectiveness (how well the medicine works) of esomeprazole (study drug) to placebo (a capsule that does not contain any medication) taken daily in relieving nighttime heartburn and problems sleeping in patients with gastroesophageal re...
What is the current status of trial NCT00660660?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 276 participants. The study started on 2008-04. Estimated completion is 2008-07.
What interventions are being tested in trial NCT00660660?
The interventions under investigation include: Placebo (DRUG), Esomeprazole (DRUG).
Who is sponsoring clinical trial NCT00660660?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00660660's enrollment target sits among peer trials
276 310th of 2000 higher than 1,690 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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