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NCT00658476 · ClinicalTrials.gov registry record · Phase 3
Omega-3 Fatty Acids for Treatment of Depression in Adolescents
A Phase 3 study, sponsored by Cedars-Sinai Medical Center.
- Completed
- Registry status
- Phase 3
- Development phase
- 4
- Enrollment target
NCT00658476: Completed Phase 3 study, sponsored by Cedars-Sinai Medical Center.
NCT00658476 is a Phase 3 study that has completed, run by Cedars-Sinai Medical Center. The registered enrollment target is 4 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00658476, a Phase 3 study, has completed, sponsored by Cedars-Sinai Medical Center.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 4 participants
- Enrollment target
Study Summary
Adolescence is the highest risk period for depression onset. More than 1.3 million youths suffer from major depression annually in the United States, and there is evidence for an increasing trend. Because many adolescents have their first depressive episode in adolescence and adolescent depression often leads to recurrent mood disorders in adults, effective treatment during early illness can minimize the negative consequences of initial and repeated episodes. Although some antidepressants (particularly Selective serotonin reuptake inhibitors (SSRIs)) are effective treatments for juvenile depression, recent warnings about suicide and the use of SSRls highlight the need for new and safe treatment for juvenile depression. Data in adults suggest that supplementation with polyunsaturated fatty acids (PUFA) might be useful for the treatment of depression. The purpose of this study is to investigate the safety and efficacy of PUFA for the treatment of adolescent depression.
Interventions
- OTHER Placebo
- BEHAVIORAL Cognitive Behavior Therapy
- DIETARY_SUPPLEMENT Fish Oil
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2006-11 |
| Est. Completion | 2009-04 |
| Phase | Phase 3 |
What the finished NCT00658476 record still lists
NCT00658476 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT00658476 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00658476 about?
NCT00658476 is a clinical study titled "Omega-3 Fatty Acids for Treatment of Depression in Adolescents". Adolescence is the highest risk period for depression onset. More than 1.3 million youths suffer from major depression annually in the United States, and there is evidence for an increasing trend. Because many adolescents have their first depressive episode in adolescence and adolescent depression o...
What is the current status of trial NCT00658476?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 4 participants. The study started on 2006-11. Estimated completion is 2009-04.
What interventions are being tested in trial NCT00658476?
The interventions under investigation include: Placebo (OTHER), Cognitive Behavior Therapy (BEHAVIORAL), Fish Oil (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT00658476?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00658476's enrollment target sits among peer trials
4 1998th of 2000 higher than 2 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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