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NCT00657813 · ClinicalTrials.gov registry record · Phase 1
Evaluation of [123I] MNI-330 and SPECT as a Marker of Beta-amyloid Protein Deposition
A Phase 1 study, sponsored by Institute for Neurodegenerative Disorders.
- Terminated
- Registry status
- Phase 1
- Development phase
- 3
- Enrollment target
NCT00657813: Clinical Trial Phase 1 study, sponsored by Institute for Neurodegenerative Disorders.
NCT00657813 is a Phase 1 study that was terminated before completion, run by Institute for Neurodegenerative Disorders. The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00657813, a Phase 1 study, was terminated before completion, sponsored by Institute for Neurodegenerative Disorders.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 3 participants
- Enrollment target
Study Summary
The main objectives of this proposal are as follows: To assess the dynamic uptake and washout of 123-I MNI-330, a potential imaging biomarker for β-amyloid burden in brain, using single photon emission computed tomography (SPECT) in similarly aged Alzheimer's (AD) subjects and healthy controls To perform blood metabolite characterization of 123-I MNI-330 in healthy and AD subjects to determine the metabolic fate and nature of metabolites in assessment of 123-I MNI-330 as a single photon computed tomography (SPECT) brain imaging agent Evaluate the test/retest reproducibility of 123-I MNI-330 and SPECT in AD subjects and healthy controls
Interventions
- DRUG MNI-330 as a brain SPECT tracer of Beta-Amyloid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2008-03 |
| Est. Completion | 2008-09-30 |
| Phase | Phase 1 |
Why NCT00657813 stopped before completion
NCT00657813 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which MNI-330 as a brain SPECT tracer of Beta-Amyloid is the first listed.
NCT00657813 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00657813 about?
NCT00657813 is a clinical study titled "Evaluation of [123I] MNI-330 and SPECT as a Marker of Beta-amyloid Protein Deposition". The main objectives of this proposal are as follows: To assess the dynamic uptake and washout of 123-I MNI-330, a potential imaging biomarker for β-amyloid burden in brain, using single photon emission computed tomography (SPECT) in similarly aged Alzheimer's (AD) subjects and healthy controls To ...
What is the current status of trial NCT00657813?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2008-03. Estimated completion is 2008-09-30.
What interventions are being tested in trial NCT00657813?
The interventions under investigation include: MNI-330 as a brain SPECT tracer of Beta-Amyloid (DRUG).
Who is sponsoring clinical trial NCT00657813?
This trial is sponsored by Institute for Neurodegenerative Disorders, which has 37 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00657813's enrollment target sits among peer trials
3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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