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NCT00655070 · ClinicalTrials.gov registry record · Early Phase 1

Effect of Timi3 Ultrasound on Myocardial Blow Flow in the Hibernating Myocardium

A Early Phase 1 study, sponsored by University of California, San Francisco.

Terminated
Registry status
Early Phase 1
Development phase
9
Enrollment target

NCT00655070: Clinical Trial Early Phase 1 study, sponsored by University of California, San Francisco.

NCT00655070 is a Early Phase 1 study that was terminated before completion, run by University of California, San Francisco. The registered enrollment target is 9 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00655070, a Early Phase 1 study, was terminated before completion, sponsored by University of California, San Francisco.

TERMINATED
Registry status
Early Phase 1
Development phase
9 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate whether the use application of low frequency ultrasound, administered by the Timi3 ultrasound device, increases myocardial blood flow to the heart, in subjects with reduced myocardial blood flow at rest (hibernating myocardium). The primary endpoint of the trial is to assess the increase in myocardial blood flow from baseline to post Timi3 Ultrasound treatment in a hypoperfused region of myocardium. Positron emission tomography (PET) imaging will be used to noninvasively evaluate cardiac blood flow. The hypothesis is that ultrasound increases blood flow in hibernating myocardium.

Interventions

  • DEVICE Timi3 Transthoracic ultrasound

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2008-04
Est. Completion 2010-12
Phase Early Phase 1

Why NCT00655070 stopped before completion

NCT00655070 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 1 intervention - of which Timi3 Transthoracic ultrasound is the first listed.

NCT00655070 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00655070 about?

NCT00655070 is a clinical study titled "Effect of Timi3 Ultrasound on Myocardial Blow Flow in the Hibernating Myocardium". The purpose of this study is to evaluate whether the use application of low frequency ultrasound, administered by the Timi3 ultrasound device, increases myocardial blood flow to the heart, in subjects with reduced myocardial blood flow at rest (hibernating myocardium). The primary endpoint of the tr...

What is the current status of trial NCT00655070?

This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 9 participants. The study started on 2008-04. Estimated completion is 2010-12.

What interventions are being tested in trial NCT00655070?

The interventions under investigation include: Timi3 Transthoracic ultrasound (DEVICE).

Who is sponsoring clinical trial NCT00655070?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00655070's enrollment target sits among peer trials

9 1745th of 2000 higher than 219 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00655070, the US trial registry maintained by the National Library of Medicine. NCT00655070 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.