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NCT00655057 · ClinicalTrials.gov registry record · Phase 2
Effects of Antidepressant Therapy on Brain Dopamine Transporter Activity in People With Major Depression
A Phase 2 study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- Phase 2
- Development phase
- 66
- Enrollment target
NCT00655057: Completed Phase 2 study, sponsored by University of Pennsylvania.
NCT00655057 is a Phase 2 study that has completed, run by University of Pennsylvania. The registered enrollment target is 66 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00655057, a Phase 2 study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 66 participants
- Enrollment target
Study Summary
This study will examine changes in brain dopamine transporter activity before and after antidepressant therapy.
Interventions
- BEHAVIORAL Cognitive behavioral therapy (CBT)
- DRUG S-citalopram
- PROCEDURE TRODAT-1 single photon emission computed tomographic (SPECT) imaging
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2005-10 |
| Est. Completion | 2009-12 |
| Phase | Phase 2 |
What the finished NCT00655057 record still lists
NCT00655057 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% lower).
The record links to 0 conditions, and to 3 interventions - of which Cognitive behavioral therapy (CBT) is the first listed.
NCT00655057 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00655057 about?
NCT00655057 is a clinical study titled "Effects of Antidepressant Therapy on Brain Dopamine Transporter Activity in People With Major Depression". This study will examine changes in brain dopamine transporter activity before and after antidepressant therapy.
What is the current status of trial NCT00655057?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 66 participants. The study started on 2005-10. Estimated completion is 2009-12.
What interventions are being tested in trial NCT00655057?
The interventions under investigation include: Cognitive behavioral therapy (CBT) (BEHAVIORAL), S-citalopram (DRUG), TRODAT-1 single photon emission computed tomographic (SPECT) imaging (PROCEDURE).
Who is sponsoring clinical trial NCT00655057?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00655057's enrollment target sits among peer trials
66 975th of 2000 higher than 1,014 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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