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NCT00654654 · ClinicalTrials.gov registry record · Phase 2
Safety and Efficacy Study of Isolagen TherapyTM in Treatment of Facial Wrinkles and Creases
A Phase 2 study, sponsored by Castle Creek Biosciences.
- Completed
- Registry status
- Phase 2
- Development phase
- 50
- Enrollment target
NCT00654654: Completed Phase 2 study, sponsored by Castle Creek Biosciences.
NCT00654654 is a Phase 2 study that has completed, run by Castle Creek Biosciences. The registered enrollment target is 50 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00654654, a Phase 2 study, has completed, sponsored by Castle Creek Biosciences.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 50 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the safety profile and the treatment effect of autologous human fibroblasts and placebo when administered to facial wrinkles and creases
Primary Outcome
Subject Wrinkle Assessment was a five point ordinal scale that assessed the subject's assessment of the appearance of their face. A score of -2 (very dissatisfied) was the worst and a score of +2 (very satisfied) was the best.
Interventions
- BIOLOGICAL Autologous Human Fibroblasts (azficel-T)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2007-03 |
| Est. Completion | 2008-06 |
| Phase | Phase 2 |
What the finished NCT00654654 record still lists
NCT00654654 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 1 intervention - of which Autologous Human Fibroblasts (azficel-T) is the first listed.
NCT00654654 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00654654 about?
NCT00654654 is a clinical study titled "Safety and Efficacy Study of Isolagen TherapyTM in Treatment of Facial Wrinkles and Creases". The purpose of this study is to evaluate the safety profile and the treatment effect of autologous human fibroblasts and placebo when administered to facial wrinkles and creases
What is the current status of trial NCT00654654?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2007-03. Estimated completion is 2008-06.
What interventions are being tested in trial NCT00654654?
The interventions under investigation include: Autologous Human Fibroblasts (azficel-T) (BIOLOGICAL).
Who is sponsoring clinical trial NCT00654654?
This trial is sponsored by Castle Creek Biosciences, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00654654's enrollment target sits among peer trials
50 1195th of 2000 higher than 740 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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