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NCT00649584 · ClinicalTrials.gov registry record · Phase 1
A Phase I Dose Escalation Study of SGN-35 Alone and in Combination With Gemcitabine for CD30-Positive Malignancies
A Phase 1 study, sponsored by Seagen.
- Terminated
- Registry status
- Phase 1
- Development phase
- 44
- Enrollment target
NCT00649584: Clinical Trial Phase 1 study, sponsored by Seagen.
NCT00649584 is a Phase 1 study that was terminated before completion, run by Seagen. The registered enrollment target is 44 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00649584, a Phase 1 study, was terminated before completion, sponsored by Seagen.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 44 participants
- Enrollment target
Study Summary
This study will examine the safety profile of SGN-35 alone and in combination with gemcitabine. The study will test increasing doses of SGN-35 given weekly to small groups of patients.
Interventions
- DRUG gemcitabine
- DRUG SGN-35
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2008-03 |
| Est. Completion | 2010-02 |
| Phase | Phase 1 |
Why NCT00649584 stopped before completion
NCT00649584 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower).
The record links to 0 conditions, and to 2 interventions - of which gemcitabine is the first listed.
NCT00649584 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00649584 about?
NCT00649584 is a clinical study titled "A Phase I Dose Escalation Study of SGN-35 Alone and in Combination With Gemcitabine for CD30-Positive Malignancies". This study will examine the safety profile of SGN-35 alone and in combination with gemcitabine. The study will test increasing doses of SGN-35 given weekly to small groups of patients.
What is the current status of trial NCT00649584?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 44 participants. The study started on 2008-03. Estimated completion is 2010-02.
What interventions are being tested in trial NCT00649584?
The interventions under investigation include: gemcitabine (DRUG), SGN-35 (DRUG).
Who is sponsoring clinical trial NCT00649584?
This trial is sponsored by Seagen, which has 84 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00649584's enrollment target sits among peer trials
44 1086th of 2000 higher than 901 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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