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NCT00647556 · ClinicalTrials.gov registry record · Phase 3
Adapalene Gel 0.3% Versus Tretinoin 0.05% Emollient Cream for Treatment of Photodamage
A Phase 3 study of Photoaging, sponsored by Galderma R&D.
- Completed
- Registry status
- Phase 3
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT00647556: Completed Phase 3 study of Photoaging, sponsored by Galderma R&D.
NCT00647556 is a Phase 3 study of Photoaging that has completed, run by Galderma R&D. The registered enrollment target is 30 participants, roughly in line with the 30-participant average among 14 other Photoaging trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00647556, a Phase 3 study of Photoaging, has completed, sponsored by Galderma R&D.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary purpose of this study is to compare the efficacy of adapalene (Differin®) gel 0.3% and tretinoin 0.05% emollient cream for the treatment of signs of photodamage, with tolerability assessment as a secondary objective.
Primary Outcome
Number of participants who improved (a decrease by at least one point) in Overall Integrated Assessment of Photodamage from baseline to week 24. Overall Integrated Assessment of Photodamage is a scale from 0 - 5 (0 = None, 1 = Minimal, 2 = Mild, 3 - Moderate, 4 = Severe and 5 = Very Severe) with 0 being best and 5 being worst.
Conditions Studied
Interventions
- DRUG adapalene gel, 0.3%
- DRUG tretinoin 0.05% emollient cream
Study Locations (1)
Michigan
- University of Michigan Department of Dermatology - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2008-04 |
| Est. Completion | 2010-01 |
| Phase | Phase 3 |
What the finished NCT00647556 record still lists
NCT00647556 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, roughly in line with the 30-participant average among 14 other Photoaging trials with a reported enrollment target.
The record links to 1 condition, with Photoaging appearing as the primary indexed condition, and to 2 interventions - of which adapalene gel, 0.3% is the first listed.
NCT00647556 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT00647556 about?
NCT00647556 is a clinical study titled "Adapalene Gel 0.3% Versus Tretinoin 0.05% Emollient Cream for Treatment of Photodamage". The primary purpose of this study is to compare the efficacy of adapalene (Differin®) gel 0.3% and tretinoin 0.05% emollient cream for the treatment of signs of photodamage, with tolerability assessment as a secondary objective.
What is the current status of trial NCT00647556?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 30 participants. The study started on 2008-04. Estimated completion is 2010-01.
What conditions does trial NCT00647556 study?
This clinical trial studies the following conditions: Photoaging.
What interventions are being tested in trial NCT00647556?
The interventions under investigation include: adapalene gel, 0.3% (DRUG), tretinoin 0.05% emollient cream (DRUG).
Who is sponsoring clinical trial NCT00647556?
This trial is sponsored by Galderma R&D, which has 158 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00647556 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Photoaging
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00647556's enrollment target sits among peer trials
30 6th of 14 higher than 8 of 14 other Photoaging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Photoaging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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