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NCT00642642 · ClinicalTrials.gov registry record · Phase 2
Safety and Efficacy Study of Autologous Fibroblasts in the Treatment of Severe Facial Acne Scarring
A Phase 2 study, sponsored by Castle Creek Biosciences.
- Completed
- Registry status
- Phase 2
- Development phase
- 122
- Enrollment target
NCT00642642: Completed Phase 2 study, sponsored by Castle Creek Biosciences.
NCT00642642 is a Phase 2 study that has completed, run by Castle Creek Biosciences. The registered enrollment target is 122 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00642642, a Phase 2 study, has completed, sponsored by Castle Creek Biosciences.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 122 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the safety profile and the treatment effect of Isolagen TherapyTM and placebo when administered to facial acne scars.
Primary Outcome
Subjects who improved by 1 point or more on the Evaluator Live Acne Scarring Assessment (ELASA), as assessed by the evaluating Investigator, are counted as responders. On the ELASA scale, a score of 0 (Clear) is best and a score of 4 (Severe) is worst.
Interventions
- BIOLOGICAL Placebo
- BIOLOGICAL Autologous Human Fibroblasts (azficel-T)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 122 participants |
| Start Date | 2007-11 |
| Est. Completion | 2009-03 |
| Phase | Phase 2 |
What the finished NCT00642642 record still lists
NCT00642642 is an interventional study that assigns participants to a tested intervention. The registered 122 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00642642 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00642642 about?
NCT00642642 is a clinical study titled "Safety and Efficacy Study of Autologous Fibroblasts in the Treatment of Severe Facial Acne Scarring". The purpose of this study is to evaluate the safety profile and the treatment effect of Isolagen TherapyTM and placebo when administered to facial acne scars.
What is the current status of trial NCT00642642?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 122 participants. The study started on 2007-11. Estimated completion is 2009-03.
What interventions are being tested in trial NCT00642642?
The interventions under investigation include: Placebo (BIOLOGICAL), Autologous Human Fibroblasts (azficel-T) (BIOLOGICAL).
Who is sponsoring clinical trial NCT00642642?
This trial is sponsored by Castle Creek Biosciences, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00642642's enrollment target sits among peer trials
122 565th of 2000 higher than 1,434 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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