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NCT00642434 · ClinicalTrials.gov registry record · Phase 4
Comparison of Blood Pressure Medications on Metabolism
A Phase 4 study, sponsored by University of New Mexico.
- Completed
- Registry status
- Phase 4
- Development phase
- 22
- Enrollment target
NCT00642434: Completed Phase 4 study, sponsored by University of New Mexico.
NCT00642434 is a Phase 4 study that has completed, run by University of New Mexico. The registered enrollment target is 22 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00642434, a Phase 4 study, has completed, sponsored by University of New Mexico.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 22 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if there are differences, (benefits) between carvedilol and metoprolol in the treatment of HTN in patients with type 2 diabetes. Specifically we will be looking at differences in blood pressure and blood sugar control, endothelial function, inflammation, oxidative stress and coagulation. Subjects will be randomized to one of the two beta-blockers and followed for 5 months. Each subject will undergo 4 inpatient studies where an oral glucose tolerance test will be done, Inflammatory and oxidative stress markers will be measured. Endothelial function will be measured using brachial artery ultrasound and laser skin Doppler
Primary Outcome
Reporting the number of participants with a change in markers of inflammation (PAI-1) following treatment compared to baseline.
Interventions
- DRUG metoprolol
- DRUG carvedilol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2004-01 |
| Est. Completion | 2008-07 |
| Phase | Phase 4 |
What the finished NCT00642434 record still lists
NCT00642434 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which metoprolol is the first listed.
NCT00642434 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00642434 about?
NCT00642434 is a clinical study titled "Comparison of Blood Pressure Medications on Metabolism". The purpose of this study is to determine if there are differences, (benefits) between carvedilol and metoprolol in the treatment of HTN in patients with type 2 diabetes. Specifically we will be looking at differences in blood pressure and blood sugar control, endothelial function, inflammation, oxi...
What is the current status of trial NCT00642434?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 22 participants. The study started on 2004-01. Estimated completion is 2008-07.
What interventions are being tested in trial NCT00642434?
The interventions under investigation include: metoprolol (DRUG), carvedilol (DRUG).
Who is sponsoring clinical trial NCT00642434?
This trial is sponsored by University of New Mexico, which has 168 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00642434's enrollment target sits among peer trials
22 1731st of 2000 higher than 259 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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