Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00639834 · ClinicalTrials.gov registry record · Phase 1

Study of the Safety of MDX-1342 in Combination With Methotrexate in Patients With Rheumatoid Arthritis

A Phase 1 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 1
Development phase
26
Enrollment target

NCT00639834: Completed Phase 1 study, sponsored by Bristol-Myers Squibb.

NCT00639834 is a Phase 1 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 26 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00639834, a Phase 1 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 1
Development phase
26 participants
Enrollment target

Study Summary

The purpose of this study is to determine if MDX-1342 given in combination with Methotrexate is a safe treatment for patients with active rheumatoid arthritis. In addition, changes in the severity patients' arthritis will also be analysed.

Interventions

  • BIOLOGICAL MDX-1342

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2008-02
Est. Completion 2010-06
Phase Phase 1
Bristol-Myers Squibb

1,025 total trials

What the finished NCT00639834 record still lists

NCT00639834 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower).

The record links to 0 conditions, and to 1 intervention - of which MDX-1342 is the first listed.

NCT00639834 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00639834 about?

NCT00639834 is a clinical study titled "Study of the Safety of MDX-1342 in Combination With Methotrexate in Patients With Rheumatoid Arthritis". The purpose of this study is to determine if MDX-1342 given in combination with Methotrexate is a safe treatment for patients with active rheumatoid arthritis. In addition, changes in the severity patients' arthritis will also be analysed.

What is the current status of trial NCT00639834?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2008-02. Estimated completion is 2010-06.

What interventions are being tested in trial NCT00639834?

The interventions under investigation include: MDX-1342 (BIOLOGICAL).

Who is sponsoring clinical trial NCT00639834?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00639834's enrollment target sits among peer trials

26 1482nd of 2000 higher than 506 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02646475 · 26 participants · Phase 1

    Metabolic Effects of Angiotensin-(1-7)

  • NCT03603223 · 26 participants · Phase 2

    Pembrolizumab in Treating Participants With Leukoplakia

  • NCT04063592 · 26 participants · NA

    AMI Construction in Lower Extremity Residual Limbs

  • NCT04906460 · 26 participants · Phase 1

    Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00639834, the US trial registry maintained by the National Library of Medicine. NCT00639834 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.